Can inhaled nitric oxide speed pneumonia recovery?

NCT ID NCT06170372

Ongoing Disease control Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences Source: ClinicalTrials.gov ↗

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This trial investigates whether adding high-dose inhaled nitric oxide to standard antibiotics can help people with pneumonia recover faster. The study includes 200 adults with hospital-acquired or community-acquired pneumonia. Participants receive either nitric oxide or a sham treatment three times daily for up to seven days, and researchers track how quickly pneumonia resolves and how the heart and lungs respond.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: inhaled nitric oxide at 200 ppm
What this could lead to: If it works, this could offer a simple add-on therapy to help people recover faster from pneumonia and reduce strain on the heart and lungs.
What could go wrong: This is an early-stage trial with no prior proof of benefit in pneumonia. High-dose nitric oxide can affect blood oxygen levels and must be carefully monitored.

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Conditions

The condition(s) this trial relates to.

Community-Acquired Pneumonia Healthcare-Associated Pneumonia nosocomial infection pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COMMUNITY-ACQUIRED PNEUMONIA NOSOCOMIAL PNEUMONIA

Contacts and locations

Locations

Cardiology Research Institute Tomsk National Research Medical Center

Tomsk, Select..., 634012, Russia

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