Can a simple gas stop pneumonia after heart surgery?

NCT ID NCT06162455

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether breathing in high-dose nitric oxide (NO) gas after heart surgery could prevent pneumonia. 74 patients who had heart surgery with a heart-lung machine were randomly assigned to receive either NO gas or a placebo (oxygen-air mixture) for 30 minutes twice a day for 5 days. The researchers measured how many patients developed pneumonia in each group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Nitric Oxide (NO) gas

What this could lead to

If it works, this could offer a simple way to prevent pneumonia after heart surgery, reducing complications and hospital stays.

What could go wrong

This is a small pilot study with only 74 participants, so results may not be definitive. The treatment requires inhaling gas twice daily for 5 days, which may be inconvenient.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NOSOCOMIAL PNEUMONIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Healthcare-Associated Pneumonia nosocomial infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cardiology Research Institute Tomsk National Research Medical Center

    Tomsk, Select..., 634012, Russia