Can a simple gas stop pneumonia after heart surgery?
NCT ID NCT06162455
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tested whether breathing in high-dose nitric oxide (NO) gas after heart surgery could prevent pneumonia. 74 patients who had heart surgery with a heart-lung machine were randomly assigned to receive either NO gas or a placebo (oxygen-air mixture) for 30 minutes twice a day for 5 days. The researchers measured how many patients developed pneumonia in each group.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- Nitric Oxide (NO) gas
- What this could lead to
- If it works, this could offer a simple way to prevent pneumonia after heart surgery, reducing complications and hospital stays.
- What could go wrong
- This is a small pilot study with only 74 participants, so results may not be definitive. The treatment requires inhaling gas twice daily for 5 days, which may be inconvenient.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cardiology Research Institute Tomsk National Research Medical Center
Tomsk, Select..., 634012, Russia
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