Breathing gas after heart surgery may stop deadly lung infection
NCT ID NCT06261827
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether breathing high-dose nitric oxide (NO) gas for 30 minutes twice a day for 5 days after heart surgery could prevent hospital-acquired pneumonia. 160 adults who had elective heart surgery with a heart-lung machine took part. Half received NO, half received a placebo (oxygen-air mixture). The goal was to see if NO lowers pneumonia rates and improves recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Nitric oxide (NO) gas
- What this could lead to
- If it works, this could offer a simple way to prevent a serious lung infection after heart surgery.
- What could go wrong
- This is a small, single-center study with no phase designation, so results may not apply widely. High-dose NO can have side effects like methemoglobinemia or lung irritation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cardiology Research Institute Tomsk national Research Medical Center
Tomsk, Russia
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Other studies related to the condition(s) this trial covers.