Breathing gas after heart surgery may stop deadly lung infection
NCT ID NCT06261827
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether breathing high-dose nitric oxide (NO) gas for 30 minutes twice a day for 5 days after heart surgery could prevent hospital-acquired pneumonia. 160 adults who had elective heart surgery with a heart-lung machine took part. Half received NO, half received a placebo (oxygen-air mixture). The goal was to see if NO lowers pneumonia rates and improves recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Nitric oxide (NO) gas
What this could lead to
If it works, this could offer a simple way to prevent a serious lung infection after heart surgery.
What could go wrong
This is a small, single-center study with no phase designation, so results may not apply widely. High-dose NO can have side effects like methemoglobinemia or lung irritation.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cardiology Research Institute Tomsk national Research Medical Center
Tomsk, Russia