Nasal spray could block COVID-19, but study halted early

NCT ID NCT05109611

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 24 times

Summary

This study tested whether a nitric oxide nasal spray could prevent COVID-19 in people at risk of exposure. About 1,389 adults were randomly assigned to use the spray or a placebo. The trial was stopped early, so final results are not available.

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Contacts and locations

Locations

  • Colombo North Teaching Hospital,

    Ragama, Sri Lanka

  • Karapitiya teaching Hospital,

    Galle, Sri Lanka

  • Medical Trust Clinics , Inc

    Oshawa, Ontario, L1G 4T3, Canada

  • National Institute of Infectious Diseases Hospital, Angoda

    Angoda, Sri Lanka

  • Peradeniya Teaching Hospital,

    Peradeniya, Sri Lanka

  • Puttalam Base Hospital,

    Puttalam, Sri Lanka

Conditions

Explore the condition pages connected to this study.