SARS COV 2 INFECTION

This study tests two experimental COVID-19 booster vaccines in 80 healthy adults aged 40-64. The vaccines are designed to create stronger and longer-lasting immune responses. Participants will receive one dose of either a vaccine or a placebo and will be monitored for side effect…

This study tests whether giving the antiviral drug remdesivir for 10 days can prevent severe COVID-19 in kidney transplant patients who have mild or no symptoms. The goal is to safely allow transplants to happen sooner, reducing time on dialysis. The trial involves 15 adults rece…

This study tests whether baricitinib, an anti-inflammatory drug, can improve thinking, physical function, and quality of life in people with long COVID. About 550 adults who had COVID-19 at least 6 months ago will receive either baricitinib or a placebo for 6 months. The main goa…

This early-stage study is testing whether specially prepared T cells from donors can help prevent COVID-19 infection in immunocompromised patients who recently received a stem cell transplant. The trial will enroll 24 children and adults to test three different dose levels for sa…

This study looks at why the immune system stays active in people with Long COVID who also have POTS (a condition causing fast heart rate upon standing). Researchers will test a drug called 2-HOBA to see if it can reduce certain immune markers. About 50 adults will take either the…

This study is creating new, safer ways to measure exercise in children with cystic fibrosis, sickle cell disease, or long-term effects from COVID-19. Current exercise tests were designed for healthy athletes and don't work well for kids with chronic conditions. Researchers will t…

This study follows 10,000 pregnant women in Nagpur, India, from early pregnancy through 42 days after birth. Researchers want to learn if catching flu, COVID-19, or other respiratory viruses raises the risk of problems like preterm labor or severe pre-eclampsia. The goal is to pr…

This study looks at why some people, mostly women, develop a fast heart rate and dizziness months after a COVID-19 infection. Researchers will measure immune system activity and nerve function in 60 participants to find possible causes. The goal is to better understand this condi…

This study aims to learn how long children under 18 stay contagious with flu, RSV, or COVID-19, and how these viruses spread to family members and classmates. Researchers will track symptoms and viral levels over time in 500 children and their households. The goal is to provide b…