SARS-COV-2 INFECTION

This study tested new versions of COVID-19 booster shots designed to protect against newer virus strains. It involved over 1,400 healthy people who had already received their initial COVID-19 vaccines. Researchers gave participants a single dose of an updated booster and then mon…

This early-stage study tested a new type of COVID-19 vaccine given as a nasal spray. Researchers enrolled 27 healthy adults aged 18-50 to receive two doses of the experimental vaccine, 56 days apart. The main goals were to check if the vaccine was safe and whether it triggered an…

This study tested a new COVID-19 booster shot in adults with conditions that weaken their immune systems, like HIV or kidney disease. The goal was to see if the extra dose was safe and helped their bodies build a stronger defense against the virus. Researchers measured antibody l…

This study tested how well the Moderna COVID-19 vaccine worked in adults with a higher risk of severe illness, including people living with HIV. Over 14,000 participants in Eastern and Southern Africa received either two or three doses, depending on whether they had a prior COVID…

This study tested a new COVID-19 booster vaccine in people who were already vaccinated. Researchers wanted to see if a single dose, given as either a shot in the arm or a nasal spray, could safely boost the body's immune defenses against the virus. They compared the new vaccine t…

This study tested a new COVID-19 booster vaccine (AVX/COVID-12) to see if it was as safe and effective at boosting immunity as an already-approved vaccine. Over 4,000 healthy adults who had previously been vaccinated against COVID-19 received either the new booster or the control…

This early-stage study tested a new COVID-19 vaccine called ABNCoV2 in 45 healthy adults who had never had COVID-19. The main goals were to check if the vaccine was safe and to find the best dose that creates a strong immune response with minimal side effects. Volunteers received…

This large study tested several versions of an mRNA vaccine to prevent COVID-19. It involved nearly 47,000 healthy volunteers, including teenagers and older adults. The main goal was to find the safest and most effective dose and schedule, leading to the authorization of the wide…

This early-stage trial tested a new investigational RNA-based COVID-19 vaccine, called BNT162b4, in 383 healthy adults who had already received previous COVID-19 shots. The main goal was to check the safety and side effects of different doses, given alone or combined with existin…

This study tested whether a single injection combining a licensed COVID-19 vaccine and a licensed flu vaccine is safe and works as well as getting two separate shots. It involved 644 healthy adults aged 50 and older. Researchers compared the combo shot to getting the vaccines sep…

This early-stage study tested three new COVID-19 RNA vaccine candidates in 72 healthy adults. It aimed to check their safety and how well they trigger an immune response in people who have never been vaccinated and in those who received previous COVID vaccines. Participants recei…

This study tested a COVID-19 booster vaccine called BIMERVAX in teenagers aged 12 to 18. Researchers wanted to see if it was safe and how well it boosted the immune system in teens who had already received two Pfizer shots. They followed 242 participants for a year, checking for …

This study tested whether a short course of the antiviral drug remdesivir could help reduce the ongoing symptoms of Long COVID. Researchers gave 73 adults with Long COVID the drug for five days and measured their symptoms before and after treatment. The main goal was to see if th…

This study tested an oral medication called S-217622 against a placebo (inactive pill) in over 2000 adults with mild-to-moderate COVID-19 who were not in the hospital. The goal was to see if the medication could help people feel better faster and reduce the amount of virus in the…

This study aimed to learn about the safety and real-world effects of the approved COVID-19 medicine Paxlovid. Over 3,300 participants aged 12 and up who were prescribed Paxlovid were followed for 28 days. Researchers watched for any side effects and checked whether their COVID-19…

This trial tested whether a combination of two existing drugs (famotidine and celecoxib) could help hospitalized COVID-19 patients recover faster and prevent severe illness in newly infected people. The study was small, with only 4 total participants, and aimed to see if this dru…

This study monitored the safety of Evusheld, a drug used to treat and prevent COVID-19 symptoms, after it was approved for use in Japan. It followed 366 Japanese patients who received the drug in real-world medical settings to track any side effects. The goal was to understand th…

This study tested new portable sensor devices designed to quickly identify infections like COVID-19, Pseudomonas bacteria, and Leishmania parasites in blood and respiratory samples. Researchers compared these new devices to standard lab tests to see if they are accurate, fast, an…

This study aimed to see if saliva tests could work as well as or better than the standard nasal swab test for finding COVID-19. Over 5,000 people who were getting a standard nasal swab test also provided a saliva sample. Researchers compared the results to see if the easier, more…

This large, completed study aimed to see if giving extra doses of the Pfizer-BioNTech COVID-19 vaccine to people who were already vaccinated was safe and effective. It involved over 16,000 healthy participants across multiple countries and tested different booster doses, includin…

This study aimed to see if taking higher daily doses of vitamin D could help prevent people from getting COVID-19. Researchers in Chicago enrolled nearly 1,500 adults and randomly assigned them to take either a standard low dose (400 IU) or a much higher dose (4,000 or 10,000 IU)…

This study tested whether two existing drugs, azithromycin and hydroxychloroquine, could prevent COVID-19 infection in hospital workers who were regularly exposed to the virus. Over 120 healthcare workers who did not have COVID-19 were randomly assigned to receive one of the drug…

This study aimed to find out which of two updated COVID-19 booster vaccines—Novavax or Pfizer's mRNA vaccine—better protects adults from getting sick with COVID-19. It also compared protection in people who got a booster to those who did not. Over 1,100 adults in Utah participate…

This study tested whether giving people a different type of COVID-19 vaccine as a booster shot (mix-and-match) works as well as or better than giving the same type they got before. It involved nearly 2,000 teens and adults in Kenya, Rwanda, and the Democratic Republic of Congo, i…

This study intentionally exposed a small group of healthy, vaccinated young adults to the Omicron BA.5 virus. The goal was to find a safe dose of the virus that reliably causes a mild infection, so researchers can better study how COVID-19 works. Participants were closely monitor…

This study aimed to understand how COVID-19 infection during pregnancy might affect the placenta, which provides oxygen and nutrients to the baby. Researchers analyzed placenta tissue and umbilical cord blood from 68 pregnant people who had COVID-19, comparing them to samples fro…

This study aimed to understand how the COVID-19 pandemic and its restrictions impacted the health and well-being of people aged 75 and older, as well as their caregivers. Researchers followed over 1,000 older adults in Spain, analyzing their health records and conducting intervie…

This study aimed to understand how COVID-19 spread in the Dominican Republic and what helped control it. Researchers followed over 1,000 people for a year, tracking their symptoms, checking their blood for past infections, and monitoring their handwashing habits. The goal was to …

This study aimed to understand why people have such different reactions to COVID-19 and influenza. Researchers collected detailed biological samples from 249 adults—some with COVID-19, some with flu, and some healthy—at different stages of illness. By analyzing this data, they ho…

This early study tested a new type of PET/CT scan in 5 people who had recovered from COVID-19. The goal was to see if a special imaging tracer could detect lung damage caused by the virus. Researchers wanted to understand if this method could help identify long-term effects in pa…

This study aimed to understand how many police officers in Bern, Switzerland, had been infected with COVID-19 and what factors increased their risk. Researchers followed over 1,000 officers for a full year, testing their blood for antibodies to see who had been exposed to the vir…

This study aimed to understand if the COVID-19 virus could persist in the lining of the nose (olfactory mucosa) in people suffering from long-term neurological symptoms like 'brain fog' after their initial infection. Researchers compared 51 adults who had COVID-19, some with last…