SARS-COV-2 INFECTION

This study tests whether an updated COVID-19 vaccine can safely protect healthy adults aged 50 to 64 from the virus. About 5,240 participants will receive either the variant-adapted vaccine or a placebo. Researchers will monitor side effects and track how many people get COVID-19…

This study tests an updated COVID-19 vaccine designed for the 2025-2026 season. It includes 760 people aged 12 and older who are at higher risk of severe COVID-19, such as those with underlying health conditions or aged 65+. Participants receive one shot, and researchers monitor …

This study tests a new vaccine designed to protect against the Omicron JN.1 variant of COVID-19. About 120 adults aged 65 and older, or those aged 12-64 with health conditions that raise their risk, will receive one shot. Researchers will check how well the vaccine boosts immunit…

This early-stage study tests a new vaccine designed to protect against many types of coronaviruses, including COVID-19 and its variants. It involves 51 healthy adults aged 18-55 who will receive two doses. The main goal is to check safety and how well the vaccine triggers an immu…

This study tests an updated COVID-19 vaccine (2025/2026 formula) in 343 children aged 5 to 11 who have health conditions that make them more likely to get very sick from COVID-19. Each child gets one shot in the arm and is followed for about 6 months. The goal is to see if the va…

This study gives healthy adults aged 18-40 who have already had a COVID vaccine or prior infection a small dose of the Omicron BA.5 virus through the nose. The goal is to find the safest dose that causes a mild, controlled infection in about half to three-quarters of participants…

This study follows 500 adults who had COVID-19 to learn about long-term health issues like breathing trouble, tiredness, and lung damage. Researchers will track recovery patterns and identify who is most at risk for lasting problems. No new treatments are tested; the goal is to b…

This study follows 1,520 mostly Black and Latinx adults in New York City who had COVID-19 to understand long-term health problems. Participants complete surveys about symptoms and allow researchers to review their medical records. A smaller group also provides blood and nasal swa…

This study follows 500 children under 18 who tested positive for flu, RSV, or COVID-19. Researchers track how long they stay contagious and how the viruses spread to family members and classmates. The goal is to provide better data for public health decisions during respiratory v…

This study follows 15,000 children and young adults (ages 0-25) with and without COVID-19 to learn why some develop long-term symptoms (long COVID). Researchers will track health, symptoms, and medical records over time. The goal is to identify risk factors and better understand …

This trial is testing a device that has not been approved by the U.S. FDA. The purpose is to collect information on how the device works and its safety in people. Participants will be monitored closely to understand the device's effects.