Could this vaccine stop future coronavirus pandemics?

NCT ID NCT06950177

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early-stage trial tests a new vaccine designed to protect against multiple coronaviruses, not just COVID-19. 51 healthy adults aged 18-55 will receive two doses to check safety and immune response. The vaccine uses a protein nanoparticle to target the virus's spike protein, aiming for broader protection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CoV-RBD-scNP-001 vaccine with 3M-052-AF adjuvant

What this could lead to

If successful, this could lead to a vaccine that protects against many different coronaviruses, including future pandemic threats.

What could go wrong

This is a very early Phase 1 trial with only 51 healthy adults, so safety and immune response are still unknown. The vaccine may not work as hoped or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

COVID-19 prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Duke University Health System

    Durham, North Carolina, 27709, United States