Scientists deliberately infect volunteers with omicron to study the virus
NCT ID NCT06478420
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study intentionally exposes healthy adults aged 18-40 who have had a COVID-19 vaccine or prior infection to the Omicron BA.5 virus via nasal drops. The goal is to find the safest dose that causes a mild, controlled infection in 50-75% of participants, while monitoring side effects and how the virus spreads. It helps researchers better understand the virus in immune-experienced people, but does not offer a treatment or cure.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre for Clinical Vaccinology and Tropical Medicine
Oxford, Oxfordshire, OX3 7LE, United Kingdom
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