MRI study seeks clues to COVID brain fog

NCT ID NCT05855434

Completed Knowledge-focused Sponsor: NHS Grampian Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed pilot study scanned the brains of 30 people who were hospitalized with COVID-19 and later reported memory, concentration, or organizational problems—often called 'brain fog.' Researchers used MRI and spectroscopy to look for changes in brain structure and chemistry that might explain these cognitive difficulties. The goal is to better understand the long-term effects of COVID-19 on the brain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help explain why some people experience 'brain fog' after COVID-19, pointing toward future ways to diagnose or treat these cognitive changes.
What could go wrong: This is a very small pilot study with only 30 participants, so results may not apply to everyone. It is observational and does not test any treatment, so it cannot directly improve symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cognitive disorder Cognitive Dysfunction COVID-19 long COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COGNITIVE CHANGE COGNITIVE DYSFUNCTION SARS-COV-2 INFECTION

Contacts and locations

Locations

Aberdeen Royal Infirmary

Aberdeen, Grampian, AB25 2ZH, United Kingdom

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