Citrus flavonoid hesperidin put to the test as a brain booster for overweight adults
NCT ID NCT07750223
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This trial tests whether a natural compound from citrus fruits, hesperidin, can improve cognitive function in overweight and obese adults aged 55 to 75. Participants take either a placebo, a low dose, or a high dose of hesperidin daily for 10 weeks. The study measures changes in memory, attention, and executive function, and also looks at gut bacteria as a possible link. The goal is to see if this simple supplement could be a nutritional way to support brain health in this population.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- hesperidin, a natural flavonoid from citrus fruits, taken as oral capsules
- What this could lead to
- If it works, hesperidin could become a simple nutritional strategy to support brain health and slow cognitive decline in people at higher risk due to excess weight.
- What could go wrong
- This is a small, early-stage trial, and results may not apply to everyone. The supplement might not improve cognition, and any benefits could be modest or short-lived.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Community Health Centers in Shanghai
RECRUITINGShanghai, Shanghai Municipality, 200030, China
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