SARS-COV-2 INFECTION

This study tests two new COVID-19 booster vaccines in 80 healthy adults aged 40-64. One vaccine includes a special ingredient called 's3' designed to boost the body's immune response. Researchers will check safety and measure how well the vaccines work against the virus.

This study tests whether a 10-day course of the antiviral drug remdesivir can prevent severe COVID-19 in kidney transplant recipients who have mild or no symptoms. About 15 adults with end-stage kidney disease who test positive for SARS-CoV-2 will receive remdesivir starting just…

This study tests whether baricitinib, an anti-inflammatory drug, can improve thinking, physical function, and quality of life in people with long COVID. About 550 adults who had COVID-19 at least 6 months ago will receive either baricitinib or a placebo for 6 months. The main goa…

This early-stage study is testing whether specially prepared T cells from donors can help prevent COVID-19 infection in immunocompromised patients who recently received a stem cell transplant. The trial will enroll 24 children and adults to test three different dose levels for sa…

This study is creating new, kid-friendly exercise tests for children with cystic fibrosis, sickle cell disease, or long-term effects of COVID-19. Current tests are designed for healthy athletes and don't work well for these children. Researchers will track 240 kids over 3-4 years…

This study looks at why some people with Long COVID develop POTS, a condition causing rapid heartbeat and fatigue. Researchers will test a drug called 2-HOBA to see if it can calm an overactive immune system. About 50 adults with Long COVID and POTS will take either the drug or a…

This study follows 10,000 pregnant women in Nagpur, India, from early pregnancy through 42 days after birth. Researchers want to learn if catching flu, COVID-19, or other respiratory viruses raises the risk of problems like preterm labor or severe pre-eclampsia. The goal is to pr…

This study looks at why some people, mostly women, develop a fast heart rate and dizziness months after a COVID-19 infection. Researchers will measure immune system activity and nerve function in 60 participants to find possible causes. The goal is to better understand this condi…