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Could a rheumatoid arthritis drug ease long COVID brain fog?

NCT ID NCT06631287

Recruiting now Disease control Sponsor: Wes Ely Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether baricitinib, a drug used for arthritis, can improve thinking, physical function, and quality of life in people with Long COVID. About 550 adults who had COVID-19 at least 6 months ago will receive either baricitinib or a placebo for 6 months. The main goal is to see if the drug helps with brain fog and other lingering symptoms.

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Conditions

The condition(s) this trial relates to.

Coronavinae infectious disease Coronaviridae infectious disease COVID-19 long COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONAVIRUS INFECTIONS COVID-19 LONG COVID SARS-COV-2 INFECTION

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Illinois Research Network (ILLInet), University of Illinois Chicago

    RECRUITING

    Chicago, Illinois, 60608, United States

  • NYU Langone Health - Brooklyn

    RECRUITING

    Brooklyn, New York, 11220, United States

  • Swedish Medical Center

    RECRUITING

    Seattle, Washington, 98104, United States

    Contact Email: •••••@•••••

  • The MetroHealth System

    RECRUITING

    Cleveland, Ohio, 44109, United States

  • University Hospitals Cleveland Case Western

    RECRUITING

    Cleveland, Ohio, 44106, United States

  • University of Arizona

    RECRUITING

    Tucson, Arizona, 85724, United States

  • University of California San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

  • University of California, Los Angeles (UCLA)

    RECRUITING

    Los Angeles, California, 90024, United States

  • University of Colorado I Anschutz Medical Campus

    RECRUITING

    Aurora, Colorado, 80045, United States

  • University of Florida College of Medicine

    RECRUITING

    Gainesville, Florida, 32610, United States

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

  • University of Texas at San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

  • Vanderbilt University Medical

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • West Virginia Clinical and Translational Science Institute

    RECRUITING

    Morgantown, West Virginia, 26506-7015, United States

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06510, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.