Heartburn and arthritis drugs tested against COVID-19

NCT ID NCT05077332

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This Phase 2 trial tested whether combining famotidine (Pepcid) and celecoxib (Celebrex) could help people with COVID-19 recover faster. Only 4 participants were enrolled, making it too small to draw firm conclusions. The study aimed to see if these drugs could reduce symptom severity and prevent hospital visits.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Famotidine (Pepcid) and celecoxib (Celebrex)
What this could lead to
If it works, this could point toward a safe, over-the-counter drug combination to help manage COVID-19 symptoms at home.
What could go wrong
This was a very small, early-phase trial with only 4 participants, so results are not reliable. The drugs may not work against COVID-19, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • US02-04: Integrated Health Solutions

    Miami, Florida, 33126, United States

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