COVID prevention drugs fail in hospital worker trial

NCT ID NCT04344379

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether hydroxychloroquine or azithromycin could prevent COVID-19 infection in hospital workers who were regularly exposed to the virus. 122 participants took one of the drugs or a placebo for 40 days. The study found no significant difference in infection rates between the groups, meaning these drugs did not prevent COVID-19.

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Conditions

The condition(s) this trial relates to.

COVID-19 prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hopial Avicenne

    Bobigny, 93000, France

  • Hôpital Broca

    Paris, 75013, France

  • Hôpital Cochin

    Paris, 75014, France

  • Hôpital GHU Paris Saclay

    Le Kremlin-Bicêtre, 92100, France

  • Hôpital La Pitié-Salpétrière

    Paris, 75013, France

  • Hôpital Necker

    Paris, 75015, France

  • Hôpital Saint Antoine

    Paris, 75012, France

  • Hôpital européen Georges Pompidou

    Paris, 75015, France