COVID prevention drugs fail in hospital worker trial

NCT ID NCT04344379

Completed Prevention Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether hydroxychloroquine or azithromycin could prevent COVID-19 infection in hospital workers who were regularly exposed to the virus. 122 participants took one of the drugs or a placebo for 40 days. The study found no significant difference in infection rates between the groups, meaning these drugs did not prevent COVID-19.

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Conditions

The condition(s) this trial relates to.

COVID-19 prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SARS-COV-2 INFECTION

Contacts and locations

Locations

Hopial Avicenne

Bobigny, 93000, France
Hôpital Broca

Paris, 75013, France
Hôpital Cochin

Paris, 75014, France
Hôpital GHU Paris Saclay

Le Kremlin-Bicêtre, 92100, France
Hôpital La Pitié-Salpétrière

Paris, 75013, France
Hôpital Necker

Paris, 75015, France
Hôpital Saint Antoine

Paris, 75012, France
Hôpital européen Georges Pompidou

Paris, 75015, France

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