One jab for two bugs: pfizer tests combo COVID-Flu vaccine
NCT ID NCT06237049
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Pfizer trial tested whether a single injection combining an updated COVID-19 vaccine and a flu vaccine is safe and triggers a strong immune response. The study involved 644 healthy adults aged 50 and older. Researchers measured side effects and antibody levels to see if the combo shot works as well as getting the vaccines separately.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Combination of a modified RNA COVID-19 vaccine and a recombinant influenza vaccine
What this could lead to
If successful, this could lead to a single annual shot that protects against both COVID-19 and flu, simplifying vaccination for older adults.
What could go wrong
This is an early-phase trial focused on safety and immune response, not yet on preventing illness. The combination may not work as well as separate shots, and side effects could be more common.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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ActivMed Practices & Research, LLC.
Portsmouth, New Hampshire, 03801, United States
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Bio-Kinetic Clinical Applications LLC DBA QPS-MO(Patient Screening Center)
Springfield, Missouri, 65807, United States
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Bio-Kinetic Clinical Applications, LLC dba QPS-MO
Springfield, Missouri, 65802, United States
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Bio-Kinetic Clinical Applications, LLD dba QPS-MO
Springfield, Missouri, 65802, United States
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Centricity Research Columbus Ohio Multispecialty
Columbus, Ohio, 43213, United States
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Charlottesville Medical Research
Charlottesville, Virginia, 22911, United States
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Clinical Research Associates Inc
Nashville, Tennessee, 37203, United States
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Clinical Research Atlanta
Stockbridge, Georgia, 30281, United States
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Clinical Research Consulting
Milford, Connecticut, 06460, United States
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Clinical Site Partners, LLC dba Flourish Research
Winter Park, Florida, 32789, United States
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Clinical Trials of Texas, LLC
San Antonio, Texas, 78229, United States
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DM Clinical Research - Bellaire
Houston, Texas, 77081, United States
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DM Clinical Research - MDC
Tomball, Texas, 77375, United States
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DM Clinical Research- Cyfair
Houston, Texas, 77065, United States
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Diablo Clinical Research, Inc.
Walnut Creek, California, 94598, United States
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East-West Medical Research Institute
Honolulu, Hawaii, 96814, United States
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GW Medical Faculty Associates
Washington D.C., District of Columbia, 20037, United States
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GW Vaccine Research Unit
Washington D.C., District of Columbia, 20037, United States
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Headlands Research Orlando
Orlando, Florida, 32819, United States
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IMA Clinical Research San Antonio
San Antonio, Texas, 78229, United States
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Indago Research & Health Center, Inc
Hialeah, Florida, 33012, United States
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JEM Research Institute
Atlantis, Florida, 33462, United States
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Las Vegas Clinical Trials
Las Vegas, Nevada, 89030, United States
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Las Vegas Clinical Trials
North Las Vegas, Nevada, 89030, United States
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Optimal Research
Melbourne, Florida, 32934, United States
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Optimal Research
Peoria, Illinois, 61614, United States
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Orange County Research Center
Lake Forest, California, 92630, United States
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Orange County Research Center
Tustin, California, 92780, United States
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Rochester Clinical Research, LLC
Rochester, New York, 14609, United States
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SMS Clinical Research
Mesquite, Texas, 75149, United States