Can antibody shots cure hepatitis b? early trial halted

NCT ID NCT05345990

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 26 times

Summary

This study tested whether giving hepatitis B antibodies (HBIG) could clear the hepatitis B surface antigen (HBsAg) from the blood of people with chronic hepatitis B. The trial aimed to enroll 20 adults who had the infection for at least a year and were already on antiviral medication. Participants received weekly antibody injections for 12 weeks. The study was terminated early after enrolling only 13 people, so results are limited.

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Contacts and locations

Locations

  • Hannover Medical School, Department for Gastroenterology, Hepatology and Endocrinology

    Hanover, Lower Saxony, 30625, Germany

Conditions

Explore the condition pages connected to this study.