Could carbon monoxide help heal lungs? small trial tests safety

NCT ID NCT04870125

First seen Jan 11, 2026 · Last updated May 11, 2026 · Updated 20 times

Summary

This early-phase study tests whether low doses of inhaled carbon monoxide can be safely given to adults with severe lung injury caused by sepsis or pneumonia. The main goal is to check safety and see if a personalized dosing formula works. Only 5 participants are enrolled, so results will be very preliminary.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Duke University Hospital

    Durham, North Carolina, 27710, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • New York-Presbyterian Brooklyn Methodist Hospital

    Brooklyn, New York, 11215, United States

  • Washington University

    St Louis, Missouri, 63110, United States

  • Weill Cornell Medical College

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.