Carbon monoxide as medicine? tiny trial tests inhaled gas for lung failure
NCT ID NCT04870125
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tested whether inhaling low doses of carbon monoxide could be safe for people with severe lung injury caused by sepsis. Only 5 participants were enrolled before the study was stopped early. The goal was to see if a personalized dosing formula could safely achieve target carbon monoxide levels in the blood.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
inhaled carbon monoxide
What this could lead to
If it works, this could point toward a new way to treat severe lung inflammation in sepsis patients.
What could go wrong
This was a very early, small safety trial that was terminated early with only 5 participants. The results are too limited to draw any conclusions about effectiveness.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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Duke University Hospital
Durham, North Carolina, 27710, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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New York-Presbyterian Brooklyn Methodist Hospital
Brooklyn, New York, 11215, United States
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Washington University
St Louis, Missouri, 63110, United States
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Weill Cornell Medical College
New York, New York, 10065, United States