Experimental cancer injection shows promise but study halted early

NCT ID NCT04725331

First seen Nov 21, 2025 · Last updated May 17, 2026 · Updated 19 times

Summary

This study tested an experimental drug called BT-001, injected directly into tumors, either alone or with the immunotherapy pembrolizumab (Keytruda). It included 31 adults with advanced solid tumors like melanoma, lung cancer, or breast cancer that had spread. The goal was to see if the treatment was safe and could shrink tumors. The study was stopped early, so results are limited.

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Contacts and locations

Locations

  • Centre Léon Bérard

    Lyon, 69008, France

  • Clinique Universitaire Saint-Luc

    Brussels, 1200, Belgium

  • Hôpital Saint-Louis AP-HP

    Paris, 75010, France

  • Institut Bergonié

    Bordeaux, 33000, France

  • Institut Gustave Roussy

    Villejuif, 94800, France

Conditions

Explore the condition pages connected to this study.