Experimental drug INB03 tested to stop COVID-19 lung decline – trial halted early

NCT ID NCT04370236

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a drug called INB03 in 79 high-risk COVID-19 patients to see if it could prevent their breathing from getting worse. Participants received two weekly injections of either INB03 or a placebo. The trial was terminated early, so we do not have clear results on whether the drug helped.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

INB03 (also called XPro1595 or Quellor)

What this could lead to

If it worked, this could point toward a treatment to prevent severe breathing problems in high-risk COVID-19 patients.

What could go wrong

The trial was terminated early with only 79 participants, so results are limited. It is unclear if INB03 is safe or effective for COVID-19.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

COVID-19 cytokine release syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baptist Clinical Research Institute

    Memphis, Tennessee, 38120, United States

  • Baptist Memorial Hospital-DeSoto

    Southard, Missouri, 38671, United States

  • Jewish Hospital

    Louisville, Kentucky, 40202, United States

  • Memorial Hermann

    Houston, Texas, 77030, United States

  • Memorial Hermann Southeast

    Houston, Texas, 77089, United States

  • Mississippi Baptist

    Kosciusko, Mississippi, 39090, United States

  • NEA Baptist

    Jonesboro, Arkansas, 72401, United States

  • Richmond University Medical Center

    Staten Island, New York, 10312, United States

  • St. Bernard's

    Jonesboro, Arkansas, 72401, United States