Real-World antibiotic study cut short: what we can learn

NCT ID NCT05487586

Terminated Knowledge-focused Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tracked how the antibiotic ceftazidime-avibactam is used in real hospital settings in China for serious infections like pneumonia and abdominal infections. Researchers planned to enroll 450 patients but the study was terminated early. The goal was to see how often the drug clears the infection and how bacteria respond, providing insights for doctors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ceftazidime-avibactam
What this could lead to: If successful, this study could provide real-world data on how well ceftazidime-avibactam works against tough hospital infections in everyday practice.
What could go wrong: This was an observational study that was terminated early, so results may be limited. It does not test a new treatment, only observes current use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Healthcare-Associated Pneumonia infectious peritonitis nosocomial infection Pneumonia, Ventilator-Associated

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COMPLICATED INTRA ABDOMINAL INFECTIONS HOSPITAL-ACQUIRED PNEUMONIA VENTILATOR ACQUIRED PNEUMONIA

Contacts and locations

Locations

Beijing Tsinghua Changgung Hospital

Beijing, China
Henan Provincial People's Hospital

Zhengzhou, China
Huashan Hospital Fudan University

Shanghai, Shanghai Municipality, 200040, China
Shanghai Tenth People's Hospital

Shanghai, China
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine

Hangzhou, China
The Affiliated People's Hospital of Ningbo University

Ningbo, China
The First Affiliated Hospital of Nanchang University

Nanchang, China
The First Affiliated Hospital of Soochow University

Suzhou, China
The First Affiliated Hospital of Xi'an Jiaotong University

Xi'an, China
The First Affiliated Hospital, Sun Yat-sen University

Guangzhou, China
The First affiliated Hospital of Anhui Medical University

Hefei, China
The Second Affiliated Hospital of Zhejiang University School of Medicine

Hangzhou, China
The Second People's Hospital of Hebei Medical University

Shijiazhuang, China
The Third Hospital of Hebei Medical University

Shijiazhuang, China
Tianjin Medical University General Hospital

Tianjing, China
Xiangya Hospital Central South University

Changsha, China
Zhongda Hospital Southeast University

Nanjing, China

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