Could a simple pill tame RSV? new trial tests obeldesivir

NCT ID NCT06585150

Terminated Disease control Sponsor: Gilead Sciences Source: ClinicalTrials.gov ↗

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This phase 2 study tests whether an oral antiviral pill called obeldesivir can safely shorten RSV symptoms in adults who are not hospitalized but are at higher risk for severe disease (e.g., those aged 60+ or with chronic lung conditions). Participants take the pill or a placebo, and researchers track how quickly their respiratory symptoms improve over 15 days. The goal is to see if this convenient treatment can help people recover faster and avoid serious complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

obeldesivir (an oral antiviral pill)

What this could lead to

If it works, obeldesivir could become a convenient at-home treatment to help high-risk adults recover faster from RSV and avoid hospitalization.

What could go wrong

This is a mid-stage trial with only 150 participants, so results may not apply to everyone. The drug may not shorten symptoms significantly or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

respiratory syncytial virus infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RSV INFECTION

Contacts and locations

Show contact details

Locations

Accel Research Sites - St. Pete-Largo Clinical Research Unit

Largo, Florida, 33777, United States
Advanced Care and Clinical Trials, LLC

Miami, Florida, 33155, United States
Aga Clinical Trials

Hialeah, Florida, 33012, United States
Agile Clinical Research Trials, LLC

Atlanta, Georgia, 30328, United States
Allianz Research Institute- Colorado

Aurora, Colorado, 80014, United States
Andres Garcia-Zuniga, MD, PA

Laredo, Texas, 78041, United States
Angels Clinical Research Institute

Miami, Florida, 33122, United States
Angels Clinical Research Institute

Tampa, Florida, 33614, United States
Be Well Clinical Studies

Lincoln, Nebraska, 78681, United States
Beautiful Minds Clinical Research Center

Cutler Bay, Florida, 33157, United States
C & A Clinical trials Corp

Cape Coral, Florida, 33990, United States
C & R Research Services USA, Inc.

Houston, Texas, 77022, United States
CCM Clinical Research Group, LLC.

Miami, Florida, 33133, United States
CCT Research- Versailles Family Medicine

Versailles, Kentucky, 40383, United States
Centennial Medical Group

Columbia, Maryland, 21045, United States
Central Alabama Research

Birmingham, Alabama, 35209, United States
Central Texas Clinical Research

Austin, Texas, 78705, United States
Clay-Platte Family Medicine/Avacare

Kansas City, Missouri, 64151, United States
Clearview Medical Research, LLC

Canyon Country, California, 91350, United States
Clinical Research Prime

Idaho Falls, Idaho, 83404, United States
Clinical Research of South Nevada

Las Vegas, Nevada, 89121, United States
Clinical Site Partners LLC dba Flourish Research

Leesburg, Florida, 34748, United States
Clinical Trial Network

Houston, Texas, 77074, United States
Clinical Trial Services, Corp

Miami, Florida, 33144, United States
Continental Clinical Research, LLC

Miami, Florida, 33144, United States
Cordova Research Institute

Miami, Florida, 33155, United States
Cullman Clinical Trials

Cullman, Alabama, 35055, United States
Diversified Medical Practices

Houston, Texas, 77057, United States
Dolphin Medical Research

Doral, Florida, 33172, United States
Doral Medical Research, LLC

Hialeah, Florida, 33016, United States
Downtown L.A. Research Center, Inc.

Los Angeles, California, 90017, United States
Dynamic Medical Research, LLC - Miami

Miami, Florida, 33144, United States
Encore Medical Research of Boynton Beach, LLC

Boynton Beach, Florida, 33436, United States
Encore Medical Research of Weston

Weston, Florida, 33331, United States
Endeavor Health - Clinical Trials Center

Skokie, Illinois, 60077, United States
Entrust Clinical Research

Miami, Florida, 33176, United States
Epic Medical Research LLC - DeSoto

Red Oak, Texas, 75154, United States
Epic Medical Research- Oklahoma

Chickasha, Oklahoma, 73018, United States
Epic Medical Research-Carrollton

Carrollton, Texas, 75006, United States
Epic Medical Research-Surprise

Surprise, Arizona, 85378, United States
Essential Clinical Research, Inc

Miami Lakes, Florida, 33014, United States
Evolution Clinical Trials

Hialeah Gardens, Florida, 33016, United States
Eximia Research-NC, LLC

Raleigh, North Carolina, 27607, United States
FOMAT Medical Research - Central Coast Family Care

Santa Maria, California, 93454, United States
Frontier Clinical Research, LLC

Morgantown, West Virginia, 26501, United States
Frontier Clinical Research. LLC Kingwood

Kingwood, West Virginia, 26537, United States
Georgetown University Medical Center

Washington D.C., District of Columbia, 20007, United States
Great Lakes Research Institute

Southfield, Michigan, 48075, United States
Hannibal Regional Healthcare System, Inc

Hannibal, Missouri, 63401, United States
Headlands Research-Scottsdale

Scottsdale, Arizona, 85260, United States
Health Awareness, LLC

Jupiter, Florida, 33458, United States
Helios Clinical Keller

Keller, Texas, 76248, United States
Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States
Indago Research & Health Center, Inc.

Hialeah, Florida, 33012, United States
Inquest Clinical Research

Baytown, Texas, 77521, United States
Jacksonville Center for Clinical Research

Jacksonville, Florida, 32217, United States
Javara Inc.

Mankato, Minnesota, 56001, United States
Kaiser Permanente Fontana Medica Center

Fontana, California, 92335, United States
L.A. Universal Research Center, INC.

Los Angeles, California, 90057, United States
LCC Medical Research Institute

Miami, Florida, 33126, United States
Lakeview Clinical Research, LLC

Guntersville, Alabama, 35976, United States
Links Clinical Trials LLC

Miami, Florida, 33176, United States
M3 Wake Research San Diego

San Diego, California, 92111, United States
Med Partners, Inc.

Toluca Lake, California, 91602, United States
Medrasa Clinical Research

Sherman, Texas, 75092, United States
Metro Infectious Disease Consultants

Burr Ridge, Illinois, 60527, United States
Metroplex Pulmonary and Sleep Center

McKinney, Texas, 75069, United States
Miami Clinical Research

Miami, Florida, 33155, United States
Monroe Biomedical Research

Monroe, North Carolina, 28112, United States
Multi-Specialty Research Associates, Inc.

Lake City, Florida, 32055, United States
NYC Health and Hospitals-Lincoln

The Bronx, New York, 10451, United States
National Institute of Clinical Research, Inc

Pomona, California, 91768, United States
Next Level Urgent Care

Houston, Texas, 77095, United States
Nuovida Research Center, Corp

Miami, Florida, 33186, United States
Nuren Medical & Research Center

Miami, Florida, 33144, United States
Oceanic Research Group

North Miami Beach, Florida, 33169, United States
P&S Research, LLC.

Miami, Florida, 33175, United States
Palm Beach Research Center

West Palm Beach, Florida, 33409, United States
Palm Springs Community Health Center

Palm Springs, Florida, 92262, United States
PanAmerican Clinical Research, LLC

Brownsville, Texas, 78520, United States
Paradigm Clinical Research

Boise, Idaho, 83709, United States
Paradigm Clinical Research

Redding, California, 96001, United States
Paradigm Clinical Research Centers, LLC., Wheat Ridge

Wheat Ridge, Colorado, 80033, United States
Precision Research Center Inc

Tampa, Florida, 33614, United States
Prestige Clinical Research Center Inc

Coral Gables, Florida, 33134, United States
Prime Global Research, Inc.

New York, New York, 10456, United States
Pro Live Medical Research

Miami, Florida, 33175, United States
Pro-Care Research Center

Miami Gardens, Florida, 33014, United States
Proactive Clinical Research, LLC

Fort Lauderdale, Florida, 33308, United States
Providence Regional Medical Center Everett

Everett, Washington, 98201, United States
Reed Medical Research

Miami, Florida, 33176, United States
Research In Miami, Inc.

Hialeah, Florida, 33013, United States
Research Institute of South Florida, Inc.

Miami, Florida, 33173, United States
Retreat Medical Research

Miami, Florida, 33135, United States
SMS Clinical Research

Mesquite, Texas, 75149, United States
Santa Clara Family Clinic

Houston, Texas, 77087, United States
Santos Research Center

Tampa, Florida, 33615, United States
Southern Clinical Research, LLC

Miami Lakes, Florida, 33014, United States
Stanford

Palo Alto, California, 94304, United States
Swedish Organ transplant and Liver Center

Seattle, Washington, 98122, United States
Sync, LLC

Hialeah, Florida, 33016, United States
The Crofoot Research Center, INC.

Houston, Texas, 77098, United States
The Lidner Research Center at The Christ Hospital

Cincinnati, Ohio, 45219, United States
Tranquil Clinical Research

Webster, Iowa, 77598, United States
Trial Management Associates, LLC

Wilmington, North Carolina, 28403, United States
UHC Research, LLC

Doral, Florida, 33126, United States
USPA Advance Concept Medical Research Group. LLC

South Miami, Florida, 33143, United States
University of California, San Francisco-Fresno

Fresno, California, 93701, United States
University of Iowa

Iowa City, Iowa, 52242, United States
University of Minnesota

Saint Paul, Minnesota, 55102, United States
Velocity Clinical Research

Lincoln, Nebraska, 68510, United States
Velocity Clinical Research

Lincoln, Nebraska, 68516, United States
Velocity Clinical Research

Norfolk, Nebraska, 68701, United States
Velocity Clinical Research - Anderson

Anderson, South Carolina, 29621, United States
Velocity Clinical Research- Suffolk

Portsmouth, Virginia, 23703, United States
Velocity Clinical Research-Salt Lake City

West Jordan, Utah, 84088, United States
Vilo Research Group, Inc

Houston, Texas, 77017, United States
WR- Global Medical Research, LLC

Dallas, Texas, 75224, United States
Wake Research

Raleigh, North Carolina, 27612, United States
Weill Cornell Medicine

New York, New York, 10065, United States
Yale University

New Haven, Connecticut, 06510, United States