CHRONIC PAIN

This study is testing whether switching to very low nicotine cigarettes helps people with chronic pain and opioid use disorder reduce their smoking. Researchers will compare these special cigarettes to regular cigarettes to see which better reduces cravings, withdrawal symptoms, …

This study is testing a comprehensive 24-week program for people who have both opioid addiction and long-term pain. The program combines standard addiction medication with therapy, exercise groups, and stress-reduction techniques like tai chi and relaxation training. Researchers …

This study is testing if pills containing THC and CBD, the main compounds in cannabis, can help people who have both chronic pain and an addiction to opioid drugs. The 147 participants are already receiving standard methadone treatment. Researchers want to see if different doses …

This study is testing if daily text messages can help people stay on their medication for opioid addiction. For six months, 60 participants will get medication reminders, and for one month, they'll also get mindfulness messages. Researchers want to see if these texts help people …

This study compares two treatments for chronic shoulder pain from rotator cuff tendinopathy. One group gets injections of platelet-rich plasma (PRP), made from their own blood, while the other gets standard steroid shots. Both groups also follow a personalized exercise program to…

This study aims to help cancer survivors who have chronic pain reduce their long-term opioid use safely. It will test four different treatment approaches, including specialized pain care and medication changes, to see which works best. The goal is to lower opioid doses by at leas…

This study is testing whether a non-invasive brain stimulation technique can help people who have both major depression and chronic pain. It will involve 54 adults who haven't gotten enough relief from standard medications. Participants will receive 30 sessions of magnetic stimul…

This study aims to implement and test culturally tailored screening and brief support for chronic pain and opioid misuse in three clinics serving American Indian and Alaska Native communities. Researchers will work with community partners to develop training for healthcare provid…

This study is testing if a mindfulness training program and regular pain management visits with a doctor can help people who have long-term pain and take opioid painkillers. The goal is to see if these approaches can reduce pain, improve daily life, and lower the risks associated…

This small, early-stage study is testing whether therapy sessions guided by the psychedelic compound psilocybin can help people with chronic pain safely reduce or stop their opioid pain medication. The study will involve 10 adults who have previously struggled to taper off opioid…

This study is testing a new approach to make a non-invasive brain stimulation treatment more effective for people with chronic pain. Researchers will use a brain scan before treatment to try to predict which patients are most likely to benefit, moving away from a one-size-fits-al…

This study is testing whether a 10-session phone or online coaching program can help people who have both chronic pain and problems with opioid use. Researchers want to see if this program helps participants manage their pain better and stay engaged in treatment for opioid use di…

This study is testing whether combining counseling support with a muscle relaxant medication can help people who regularly use opioids for chronic back or neck pain safely reduce their medication after spine surgery. Researchers will compare three approaches in 375 patients acros…

This study is testing whether a special training program for doctors and other healthcare providers can help people with long-term chronic pain. The training teaches providers new ways to manage pain without relying as heavily on opioid medications. Researchers will measure if pa…

This study is testing whether a non-invasive brain stimulation device can help people with opioid addiction and chronic pain. The device uses a combination of mild electrical and ultrasound stimulation. Researchers will measure if it helps participants reduce their drug use and m…

This study is testing three different treatments to help people who have been taking prescription opioids for chronic pain for a long time. The goal is to see if adding a buprenorphine patch, a type of counseling called cognitive behavioral therapy, or a non-invasive brain stimul…

This study is testing a new pain assessment tool to see if it can predict which patients with chronic pancreatitis will get relief from standard endoscopic or surgical treatments. Researchers will enroll 150 adults with chronic pancreatitis who are already scheduled for one of th…

This study is testing a new computer algorithm designed to help diagnose chronic pain. It compares the algorithm's recommendations to those made by expert pain doctors. About 200 people with chronic pain will answer an online questionnaire, and researchers will check how well the…

This study aims to prevent acute pain from developing into long-term chronic pain by treating PTSD symptoms early. Researchers will enroll 345 adults with PTSD who arrive at the emergency room or clinic with new, non-injury pain. Participants will be randomly assigned to receive …

This study is testing a coaching program designed to help Black patients who have both long-term pain and depression. The program uses four coaching sessions to help people learn about and stick with non-drug treatments, like physical therapy or mindfulness, and to talk more effe…

This small pilot study is testing an online therapy program designed to help women with endometriosis manage their chronic pain. Ten participants will work through a guided program focused on mindfulness, acceptance, and changing behaviors related to pain. The goal is to see if t…

This study is testing an online self-help program designed to help people with chronic pain. The program uses Acceptance and Commitment Therapy (ACT) to teach skills for accepting pain and focusing on living a meaningful life. Researchers will compare the program to a waitlist gr…

This early-stage study is testing a faster form of brain stimulation to help people with long-term chronic pain. Researchers will use a special AI algorithm to find the best spot on each person's brain to target with magnetic pulses. The goal is to see if this personalized approa…

This study is testing whether a behavioral therapy that improves sleep can also help reduce pain and lower the use of opioid pain medication. It will involve 165 adults who have chronic pain, trouble sleeping, and are currently prescribed opioids. Researchers believe that by impr…

This study compares different pain relief approaches after a minimally invasive elbow tendon procedure. Researchers want to see if common anti-inflammatory drugs (NSAIDs) work as well as opioid painkillers for managing post-procedure pain. The goal is to find effective pain contr…

This study is testing if a single 2-hour class teaching pain management skills works better than standard care alone for reducing pain after joint or bone surgery. It will enroll 134 adults who have had chronic pain before their elective surgery. Researchers will compare pain lev…

This study is testing whether a specific type of talk therapy, called Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), can help veterans who have both serious mental illness and chronic back pain. Researchers will compare the therapy to a general health education program i…

This study is testing two different community-based group programs to see which one better helps people manage chronic back or neck pain. Participants will be randomly assigned to attend one of two 9-week programs: one focuses on mind-body skills like mindfulness, while the other…

This study is testing two different brief talk therapy programs to help adults manage chronic pain. Researchers are comparing a mindfulness-based approach with a cognitive-behavioral therapy approach, with both available in English and Spanish. The goal is to see which approach w…

This study aims to see which of two different nerve-block injection techniques is better at preventing long-term (chronic) pain after breast removal surgery (mastectomy). Researchers will compare a pectoral nerve block to a paravertebral block in 90 female patients. The goal is t…

This study is testing a two-week, completely remote treatment program for people suffering from both chronic pain and PTSD. Researchers want to see if combining a mild, non-invasive brain stimulation technique with a specialized talk therapy is more effective than the therapy alo…

This study is testing if the compound CBD (cannabidiol) can safely help people who have both opioid addiction and long-term pain. Researchers will give different doses of CBD to 34 people who are already receiving standard medication treatment for their addiction. They will measu…

This study is testing whether combining physical exercise with short educational sessions about how pain works is better at helping older adults manage long-term pain than exercise alone. It involves 100 people aged 65+ who have had pain for over 3 months. Participants are random…

This study is testing whether a 12-week supervised strength training program can reduce chronic pain in people with multiple sclerosis (MS). Researchers will compare pain levels in 116 participants who either start the exercise program right away or continue with their usual care…

This pilot study is testing a culturally adapted mindfulness program called 'Quiet Focus' for older Black adults who experience both chronic pain and depression. The research aims to see if this tailored therapy is a practical and acceptable approach for this community. The main …

This study is testing whether an 8-week program held in a university museum can help women with fibromyalgia. The program combines art appreciation, mindfulness, and gentle movement exercises. Researchers want to see if this unique approach reduces widespread pain and improves da…

This study aims to find out which of two common treatments works better for people with long-lasting tailbone pain (coccydynia). Researchers will compare hands-on osteopathic therapy with a targeted nerve-block injection. The goal is to see which one reduces pain and improves dai…

This study tests a walking program designed to help people with painful hip or knee osteoarthritis become more active. Participants take common anti-inflammatory pain medication only before planned walks, combined with proper footwear and education, to reduce pain during movement…

This study is testing a new pattern of electrical pulses delivered by an approved spinal cord stimulator to see if it better manages chronic pain. It will enroll about 70 adults who have had back or leg pain for at least 6 months. The main goal is to see how many people can cut t…

This study is testing a very brief, 4-session cognitive behavioral therapy (CBT) program designed to help people manage the symptoms of urologic chronic pelvic pain syndrome (UCPPS). Researchers are comparing this short therapy to a basic education program in 240 adults diagnosed…

This study is testing a non-invasive skin patch that delivers gentle electrical pulses to try to reduce chronic nerve pain caused by shingles, known as postherpetic neuralgia. It will involve 35 adults who still have pain despite standard treatments. Researchers will check if the…

This study tests a 6-month phone and video call program designed to help older adults with chronic knee or hip arthritis pain. The program coaches participants on increasing daily movement, reducing sitting time, and healthy eating to manage weight. Researchers want to see if thi…

This study is testing whether combining mindfulness training with open-label placebo pills (sugar pills patients know are placebos) is a practical and acceptable way to help people with chronic pain. Researchers will recruit 45 adults with ongoing pain to try either mindfulness c…

This study is testing whether a pill containing synthetic THC (the main active compound in cannabis) can help reduce chronic low back pain. About 75 adults with long-term back pain will take either the THC pill or a placebo (sugar pill) daily for 8 weeks. The main goal is to see …

This study is testing a new group therapy delivered over Zoom to help adults who have both chronic pain and opioid use disorder. The therapy focuses on understanding and expressing emotions to reduce pain, disability, and opioid-related problems. Researchers want to see if this a…

This study aims to see if adding ozone therapy improves the quality of life for adults with severe, treatment-resistant chronic pain and related symptoms. Researchers will observe about 105 patients who are already being treated with ozone at a specialized pain clinic. They will …

This study is testing whether a new type of talk therapy can help people who still have pain months after a serious bone or muscle injury. About 30 participants will attend 8 weekly therapy sessions focused on emotional awareness and expression. The main goal is to see if this ap…

This study is testing a new program called SCOOP, which uses weekly coaching sessions and videos to teach older adults in rural areas how to better manage chronic pain and increase social connections. Researchers want to see if the program helps reduce how much pain interferes wi…

This pilot study is testing whether a flexible, stepped care program is a practical and acceptable way to help people who have both chronic pain and PTSD. Researchers will compare this new approach to usual care in two primary care clinics. The main goal is to see if the program …

This study is testing a new virtual program designed to help teenagers with long-term muscle or joint pain become more physically active and build resilience. The program involves four weekly online sessions that teach motivation, confidence, and pain coping skills. Researchers w…

This study is testing a new approach to spinal cord stimulation, a common treatment for chronic pain. Researchers want to see if they can improve pain relief by using a device that 'listens' to the body's nerve signals in real-time to automatically adjust the stimulation. They ar…

This study is testing whether virtual reality (VR) therapy can help people with long-term low back pain. Researchers are comparing two different VR approaches—one focused on distraction and another on building pain-management skills—to see which works better. The goal is to reduc…

This study is testing whether online yoga classes work as well as an established therapy (Acceptance and Commitment Therapy) for reducing chronic pain in veterans. 274 participants will be randomly assigned to attend either online yoga or therapy classes once a week for 12 weeks.…

This study is testing if a device that sends electrical pulses to the spinal cord can help reduce leg pain in people who have both painful diabetic nerve damage and poor blood circulation. Up to 15 participants who already have the device implanted will try two weeks of real stim…

This study is testing whether a small, battery-powered headband that delivers a gentle electrical current can reduce chronic pain in people receiving regular kidney dialysis. The trial will enroll 125 adults with end-stage kidney disease who experience significant pain, aiming to…

This study is testing whether a smartphone app called QoLibri can help people with long-term chronic pain improve their daily lives. Researchers will compare the app's effects to a waiting list control group in about 410 participants. The main goal is to see if using the digital …

This small pilot study is testing whether a new, combined virtual therapy can help people who suffer from both PTSD and chronic pain. The treatment blends two proven therapies into 12 online sessions to address both conditions at the same time, rather than one after the other. Re…

This study is testing whether mind-body therapy can help people with chronic back pain. Researchers will compare two different mind-body approaches against standard medical care to see which works best at reducing pain and improving daily function. The study aims to enroll 150 ad…

This study is testing a smartphone app designed with input from teens to help them manage long-term chronic pain. The app teaches coping skills like relaxation and managing negative thoughts, based on proven psychological therapies. Researchers will measure if using the app reduc…

This study is testing whether four virtual coaching sessions can help veterans with chronic pain use their own cannabis products more effectively. The research aims to see if this coaching improves pain management, sleep, anxiety, and overall quality of life. The study will enrol…

This study is testing a single, two-hour online class taught in Spanish that provides skills to help manage chronic pain. Researchers want to see if this class is helpful and easy to use for Spanish-speaking adults who have had pain for at least three months. Participants will be…

This small pilot study is testing a smartphone app called 'Mindful Journey' to see if it's helpful and easy to use for adults who are in recovery from opioid addiction and also have chronic pain. The app delivers short, on-the-spot mindfulness videos and exercises to help people …

This VA study is testing whether adding Whole Health Coaching to standard pain management helps veterans with chronic pain. The coaching focuses on personal health goals across eight areas of wellness to improve daily function and reduce opioid-related safety concerns. Researcher…

This study is testing whether a special pain clinic, where a team of five different specialists works together, can help Veterans with long-term pain. Researchers want to see if patients report less pain and if pain interferes less with their daily lives after six months in the p…

This study is testing two different phone-based programs to see which one better helps people with HIV who also have chronic pain and insomnia. One program focuses on building better sleep habits, while the other teaches mindfulness techniques. Researchers want to see if these pr…

This early-stage study is testing whether adding an existing epilepsy drug, lacosamide, to standard opioid painkillers is safe and tolerable for adults with chronic pancreatitis. The main goal is to see if the combination helps reduce severe abdominal pain and might allow patient…

This study is testing whether Scrambler Therapy, a non-invasive device that delivers gentle electrical signals through the skin, can help reduce severe abdominal pain in adults with chronic pancreatitis. About 40 participants who still have pain despite standard treatments will r…

This small pilot study is testing whether playing music for patients during common back pain injections can help them feel less anxious and experience less pain. Researchers will compare anxiety and pain scores between a group that listens to music and a group that does not. The …

This study is testing a new, non-drug device called the Sana Pain Reliever to see if it can reduce chronic pain in people with Post-treatment Lyme Disease. The device is a special mask with earbuds that pulses light and plays tones for 15-minute sessions at home. Researchers will…

This study is testing an online therapy program designed to help people who have both PTSD and long-term pain. It will involve 40 participants who will either start the program right away or after a 12-week wait. The goal is to see if this internet-delivered therapy can reduce sy…

This study is testing a gentle, non-invasive ultrasound technique on the brain to see if it can help people who struggle with chronic back pain, opioid addiction, and anxiety. Researchers will measure changes in pain levels, drug cravings, anxiety, and vital signs like heart rate…

This study is testing whether group-based treatments can help low-income patients better manage chronic pain. Researchers will compare group medical visits and group acupuncture to usual care in community health clinics. The goal is to see if these approaches reduce pain's impact…

This study is testing whether combining chiropractic care with virtual group support sessions can help adults 65 and older manage chronic spine pain. Researchers want to see if this combined approach is practical and acceptable to participants. The small pilot study will enroll 1…

This study is testing if metformin, a common diabetes medication, can help reduce pain and improve healing in people with chronic Achilles tendon problems. Forty participants with this condition will take either metformin or a placebo pill for 16 weeks while also doing a home exe…

This small pilot study is testing whether a mind-body therapy program can help people with long-term pain in their wrists, elbows, or shoulders from repetitive stress. Researchers will see if the program improves arm function, reduces pain intensity, and lowers pain-related anxie…

This study is testing whether adding virtual reality (VR) to standard neck exercises helps people with chronic neck pain or whiplash feel better. 72 participants will do rehab exercises twice a week for six weeks, with half using a VR headset and half doing the same exercises wit…

This study is testing whether a yoga-based occupational therapy program can help teenagers with chronic pain. Researchers want to see if the therapy improves the teens' awareness of their body's signals and their ability to do daily activities. About 49 adolescents, aged 11 to 21…

This study is testing two different methods to manage pain after total knee replacement surgery. Researchers want to see if using a small, temporary catheter that continuously delivers numbing medicine to the leg is better than a standard single injection at reducing the need for…

This study is testing whether a very brief, 7-minute mindfulness session can help reduce pain and anxiety for people undergoing specific spine procedures called kyphoplasty or radiofrequency ablation. Researchers will enroll 80 patients and randomly assign them to either receive …

This study is exploring whether a mindfulness program can be adapted and delivered using virtual reality (VR) to help veterans with spinal cord injuries manage chronic pain. Researchers will first work with a small group of veterans to identify needed changes to the program, then…

This study is testing whether a combination of non-drug therapies can help reduce chronic back and neck pain in military personnel and their families. It will involve 125 participants who will receive treatments like acupuncture, laser therapy, and massage at a military clinic. T…

This study is testing if adding a simple sugar solution (dextrose) to a standard numbing injection can better relieve chronic pain from knee osteoarthritis. Researchers will compare the sugar-water mix against the numbing medicine alone in 60 adults with persistent knee pain. The…

This study is testing whether two types of noninvasive brain stimulation can reduce chronic pain in people with carpal tunnel syndrome. Researchers will compare real stimulation to fake stimulation in 95 adults who have had persistent hand pain for at least six months. The goal i…

This study is testing whether regular manual therapy sessions are better than self-exercise education for reducing chronic neck pain. Researchers will compare two groups of 125 adults with long-term mild neck pain over 20 weeks. The goal is to see which approach provides better p…

This study is testing if adding Shiatsu therapy to regular treatment helps children and teenagers with long-lasting pain feel better and improve their quality of life. About 40 participants, aged 10 to 18, will receive weekly Shiatsu sessions for six weeks while continuing their …

This study is testing whether a smartphone-based mindfulness program is practical and helpful for teens and young adults with sickle cell disease. Participants will use the app for about 8 weeks to try to manage their chronic pain and sleep problems. The main goal is to see if pe…

This small, early-stage study is testing whether a mind-body intervention can help people with frequent migraines. Researchers are recruiting 10 adults to try the remote program and provide feedback. The main goal is to see if the approach is practical and to gather information f…

This study is testing whether a skin patch containing capsaicin, the compound that makes chili peppers hot, can reduce chronic nerve pain in teenagers. It will compare the capsaicin patch to a placebo patch in 46 teens aged 12 to 17 who have had pain for over 3 months following s…

This study is testing whether taking methadone twice a day instead of once a day helps people better manage chronic pain while being treated for opioid addiction. It will involve 150 adults already receiving stable methadone treatment. Researchers will compare pain levels and tre…

This study is testing whether a combination of herbal supplements and vitamin IV (intravenous) therapy can help reduce symptoms for people with conditions like anxiety, chronic pain, fibromyalgia, arthritis, and high blood pressure. It will enroll 25 participants to see if these …

This study is testing whether group counseling can help people who feel shame or stigma because of their health condition. Researchers are enrolling 195 adults with conditions like obesity, cancer, HIV, diabetes, or chronic pain who report feeling stigmatized. Participants will t…

This study is testing whether a short, audio-guided mindfulness practice can help reduce pain for patients waiting in an orthopedic clinic. Researchers will compare the mindfulness audio to standard injury management information. The goal is to see if this brief, accessible inter…

This study is testing whether a specific, long-term exercise program can help U.S. veterans feel better. It will see if the workouts improve body composition, physical strength, and reduce symptoms of pain, fatigue, depression, and PTSD. Over 18 months, 25 participants will atten…

This study tests whether freezing specific nerves around the knee at least 24 hours before total knee replacement surgery can reduce long-term pain and improve recovery. About 100 adults with knee osteoarthritis will be randomly assigned to receive either the nerve-freezing proce…

This study is testing whether a 10-week program combining gentle walking goals with mind-body skills (like breathing exercises and mindfulness) can help older adults with chronic musculoskeletal pain move more easily and feel better. The program, called GetActive+, is being compa…

This study is testing whether a specially adapted phone app that teaches pain management skills is more helpful than standard pain education for reducing chronic pain in teen survivors of childhood cancer. It will involve 204 participants (teens and their caregivers) across four …

This study is testing a personalized, non-invasive brain stimulation technique to see if it can help reduce chronic pain. Researchers will recruit 144 adults with long-term pain that hasn't responded well to other treatments. Participants will receive either real or placebo stimu…

This study is testing whether offering yoga or physical therapy classes directly at opioid treatment centers can help people who are dealing with both chronic back pain and opioid use disorder. Researchers will compare these two programs to usual care to see which one better redu…

This study is testing whether a smartphone app can help Black and LGBTQ+ adults better manage their chronic pain. Researchers want to see if using the app is practical and helpful for 300 people who have had pain for at least 3 months that interferes with daily life. The app teac…

This study is testing whether spinal cord stimulators can be adjusted remotely to better control chronic back and leg pain. Fifteen adults already scheduled to get a spinal cord stimulator will try different stimulation patterns through a smartphone app over four months, reportin…

This study aims to understand how a Boswellia serrata supplement might work to reduce pain. Researchers will give the supplement or a placebo to 12 healthy volunteers and then use a capsaicin (hot pepper) patch to create temporary pain and sensitivity on the skin. They will measu…

This study aims to understand how daily pain, mood, and activities are connected by having 800 participants use a smartphone app called SOMA for four months. The goal is to find patterns that might predict when short-term (acute) pain becomes long-term (chronic) pain. A smaller g…

This study aims to find out what factors predict whether someone with sickle cell disease will develop severe, long-lasting pain. Researchers will follow 70 participants, aged 15-40, for up to four years, using surveys and pain sensitivity tests. The goal is to gather information…

This study aims to understand if a hormone called oxytocin affects a specific type of pupil movement (hippus) as a way to measure brain activity. Researchers will compare healthy volunteers to people with chronic knee pain from arthritis. Participants receive either oxytocin or a…

This study aims to understand why people with chronic pain find it harder to quit smoking. Researchers will use brain scans and smartphone surveys to see how temporary smoking withdrawal changes pain signals in the brain and affects quit attempts. The goal is to gather informatio…

This study aims to understand chronic jaw pain by looking at how different areas of the brain communicate. Researchers will use MRI brain scans on about 95 women with and without chronic jaw pain to see if specific brain connection patterns are linked to how disabling the pain is…

This study aims to understand why people with similar knee arthritis damage experience very different levels of pain, especially when walking. Researchers will recruit 300 adults with chronic knee pain to complete surveys, walking tests, knee scans, and non-invasive brain imaging…

This study aims to understand how different types of spinal cord stimulation (some with a tingling sensation, some without) relieve chronic nerve pain. Researchers will use brain scans and pain tracking in 90 patients to learn how these treatments work in the body and to identify…

This study aims to understand why some people develop long-term pain after surviving a serious illness in the Intensive Care Unit (ICU). Researchers will follow 800 Danish ICU survivors for up to a year, asking about their pain, sleep, mood, and quality of life. The goal is to id…

This study aims to understand how chronic nerve pain affects the brain's reward system and motivation. Researchers will compare brain scans and learning tasks in 50 people with chronic pain against healthy volunteers. The goal is to learn why pain can reduce motivation, not to te…

This study aims to understand how long-term opioid use and chronic pain change activity in the brain and spinal cord. Researchers will use MRI scans, questionnaires, and simple tests to compare women with these conditions to healthy women. The goal is to gather knowledge that cou…

This study aims to understand why some children develop long-lasting pain after common surgeries. Researchers will follow 5,000 children, aged 0-16, for a year after their operations using questionnaires. The goal is to identify risk factors so doctors can better prevent and mana…

This study aims to understand if a system giving fake feedback in a virtual reality (VR) environment can change specific brain waves linked to attention control. Researchers will measure brain activity in 35 adults with conditions like rumination or chronic pain while they experi…

This study aims to map and understand nerve-related issues like numbness, tingling, and pain in patients who were treated for mouth or throat cancer 1 to 5 years ago. Researchers will examine 120 patients during their regular follow-up visits to document these sensations and thei…

This study is testing new digital chat software designed to collect detailed health information from people with chronic pain. Researchers want to see if these tools are easy to use, practical, and acceptable for patients to share information about their physical symptoms, emotio…

This study aims to collect real-world information from patients who use or plan to use an approved medical device or procedure for chronic pain. It will track how their pain levels change over time after the procedure. The goal is to better understand how these treatments work in…

This study aims to better understand the chronic pain experienced by people with pancreatitis. Researchers will use a special pain mapping test on 500 participants, including healthy volunteers and patients, to see if certain pain patterns can predict who will benefit from treatm…

This study aims to collect real-world safety and effectiveness data on Abbott's implanted neurostimulation devices for chronic pain. It will follow 2,000 patients for up to five years after they receive the device to track any side effects and how well it works over time. The goa…

This study aims to understand how spinal cord stimulation (SCS) helps people with chronic nerve pain. Researchers will measure specific chemicals in the blood and spinal fluid of 30 patients before and after they receive SCS treatment. The goal is to learn how SCS works at a biol…

This study aims to gather information to help design and run a new type of chronic pain clinic that uses a whole-person approach. Researchers will observe 120 people with long-term pain, tracking their pain levels, medication use, and overall well-being. The goal is not to test a…

This study aims to learn which treatments work best for chronic pain by looking back at the anonymous medical records of 15,000 people. Researchers will not give any new treatments; they will only review past outcomes from different approaches. The goal is to gather knowledge to …

This study aims to understand if using a CPAP machine to treat obstructive sleep apnea can also help reduce chronic pain. Researchers will follow 80 people newly diagnosed with sleep apnea as they start CPAP therapy, tracking their pain levels and CPAP use over 6 months. The goal…