Pepper patch could soothe teen nerve pain without pills

NCT ID NCT05997979

Recruiting now Symptom relief Sponsor: University Hospital, Brest Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a capsaicin 8% patch (made from chili pepper extract) can reduce chronic nerve pain in teenagers aged 12 to 17 who have had pain for over 3 months after surgery or injury. Half the teens get the real patch, the other half get a placebo dressing. Pain levels are checked before treatment and again 4 months later. The goal is to see if the patch offers better pain relief than a dummy treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: capsaicin 8% patch (QUTENZA®)
What this could lead to: If it works, this could offer a new, non-drug option to ease chronic nerve pain in teenagers after surgery or injury.
What could go wrong: This is a small early-phase trial with only 46 teens, so results may not apply to everyone. The patch can cause skin irritation or burning, and pain relief may not be long-lasting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome neuralgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC PAIN NEUROPATHIC PAIN

Contacts and locations

Locations

CHU d'Amiens
RECRUITING

Amiens, France
CHU d'Angers
RECRUITING

Angers, France
CHU de Bordeaux
RECRUITING

Bordeaux, France
CHU de Brest
RECRUITING

Brest, France
CHU de Lyon
RECRUITING

Lyon, France
CHU de Marseille
RECRUITING

Marseille, France
CHU de Montpellier
RECRUITING

Montpellier, France
CHU de Nantes
RECRUITING

Brest, France
CHU de Tours
RECRUITING

Tours, France
Institut Gustave Roussy
RECRUITING

Villejuif, France

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