Can a tiny catheter cut opioid use after knee surgery?
NCT ID NCT05981105
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study compares two ways to manage pain after total knee replacement: a continuous nerve catheter that delivers numbing medicine for days versus a single nerve block. Sixty-four adults scheduled for knee surgery will be randomly assigned to one of the two methods. Researchers will track how much opioid pain medication they need and whether they develop chronic pain up to six months later.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ropivacaine
What this could lead to
If it works, this could provide a better way to manage pain after knee replacement, reducing opioid use and long-term pain.
What could go wrong
This is a small, early-stage study with only 64 participants, so results may not apply to everyone. The catheter may cause infection or discomfort.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital for Special Surgery
RECRUITINGNew York, New York, 10021, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-••••