Can a tiny catheter cut opioid use after knee surgery?

NCT ID NCT05981105

Recruiting now Symptom relief Sponsor: Hospital for Special Surgery, New York Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares two ways to manage pain after total knee replacement: a continuous nerve catheter that delivers numbing medicine for days versus a single nerve block. Sixty-four adults scheduled for knee surgery will be randomly assigned to one of the two methods. Researchers will track how much opioid pain medication they need and whether they develop chronic pain up to six months later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ropivacaine
What this could lead to: If it works, this could provide a better way to manage pain after knee replacement, reducing opioid use and long-term pain.
What could go wrong: This is a small, early-stage study with only 64 participants, so results may not apply to everyone. The catheter may cause infection or discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ADDUCTOR CANAL BLOCK are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome opioid abuse osteoarthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADDUCTOR CANAL BLOCK CHRONIC PAIN OPIOID USE TOTAL KNEE ARTHROPLASTY

Contacts and locations

Locations

Hospital for Special Surgery
RECRUITING

New York, New York, 10021, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.