New approach aims to help chronic pain patients cut opioids after surgery

NCT ID NCT06027099

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 29 times

Summary

This study tests whether combining counseling with a muscle relaxant (tizanidine) can help people who have used opioids for a long time reduce their painkiller use after elective surgery. About 375 adults aged 18–75 will be randomly assigned to receive the combined treatment, counseling plus a placebo, or standard care. The goal is to see if the intervention helps them return to their pre-surgery opioid level faster and lowers the risk of opioid misuse.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Atrium Health Wake Forest Baptist Medical Center

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Harvard University- Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford University Medical Center

    RECRUITING

    Stanford, California, 94305, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Kansas Medical Center

    RECRUITING

    Kansas City, Kansas, 66103, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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