One dose or two? study aims to ease pain for people on methadone

NCT ID NCT05459402

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether taking methadone once a day or twice a day works better for people who have both chronic pain and opioid use disorder. About 150 adults currently on methadone treatment will be randomly assigned to one of the two dosing schedules. Researchers will track pain levels and tolerance over 12 weeks to find the best approach.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Addiction Treatment Services (ATS)

    RECRUITING

    Baltimore, Maryland, 21224, United States

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