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Ear-Zapping device may ease pain and opioid withdrawal

NCT ID NCT05555485

Recruiting now Symptom relief Sponsor: The University of Texas Medical Branch, Galveston Source: ClinicalTrials.gov ↗

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study tests a wearable device worn on the ear that stimulates nearby nerves to change brain signals. The goal is to see if it can reduce chronic pain and ease symptoms of opioid withdrawal. Adults aged 18 to 65 with chronic pain who are tapering off opioid medication will receive either real or fake stimulation over two days. Researchers will measure withdrawal symptoms, pain levels, and brain activity using MRI.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
transcutaneous auricular neurostimulation device (Sparrow)
What this could lead to
If it works, this could offer a drug-free way to manage chronic pain and reduce opioid withdrawal symptoms.
What could go wrong
This is a small, early-stage study with only 60 participants. The device may not work better than a sham (fake) treatment, and individual results may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

agnosia chronic pain syndrome pain agnosia substance withdrawal syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANALGESIA OPIOID WITHDRAWAL

Contacts and locations

Locations

  • University of Texas Medical Branch

    RECRUITING

    Galveston, Texas, 77555, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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