The University Of Texas Medical Branch, Galveston

This study tests whether peer coaching can help older adults (55+) with uncontrolled type 2 diabetes in rural Kentucky better manage their condition. Participants are paired with trained peer coaches who call them weekly or bi-weekly to discuss self-care and goals. The study will…

This study tests whether regular phone calls from a trained peer coach can help older adults (55+) with type 2 diabetes in rural Kentucky improve their self-care. Participants are divided into groups that receive weekly or bi-weekly coaching calls to discuss goal-setting and diab…

This study compares a minimally invasive procedure called middle meningeal artery embolization (MMAE) to standard open surgery for treating chronic subdural hematoma, a type of brain bleed. About 520 moderately symptomatic adults aged 40-90 will be randomly assigned to one of the…

This pilot study tests whether tirzepatide (Zepbound), a drug already used for weight loss, can slow biological aging in adults aged 55 to 70. Ninety participants with a BMI of 27 or higher will be randomly assigned to receive the drug weekly for 24 weeks or no drug, followed by …

This study looks at whether involving family members can help people with type 2 diabetes in rural Kentucky eat healthier and exercise more. Researchers will work with 75 participants and their families to create a personalized nutrition and physical activity plan for 6 months. T…

This study compares the immune response from 2 doses versus the standard 3 doses of the HPV vaccine in women aged 27-45. About 618 participants will be randomly assigned to receive either 2 or 3 doses, and their antibody levels will be checked over 12 months. If 2 doses prove non…

This study looks at whether a 12-week home-based strength training program, supported by technology and telehealth, is practical for 20 adults aged 55-80 with type 2 diabetes and mild cognitive impairment. Participants will start with supervised sessions and gradually exercise on…

This study compares three methods to reduce pain during corticosteroid injections for arthritis, tendinopathy, or nerve compression in the hand, wrist, or elbow: no anesthesia, a vibrating device, or a cooling spray. Each participant will receive two of the three methods to see w…

This study tests whether dry needling—a technique where thin needles are inserted into muscles—can reduce pain and improve quality of life for people with chronic low back pain. Researchers will also check if the approach is practical and acceptable. The study includes 42 adults,…

This study tests a telerehabilitation program that uses technology to help adults recovering from burns. Participants will do rehab exercises at home with remote guidance. The goal is to see if this approach improves joint range of motion and scar quality. The study enrolls 30 ad…

This study tests whether eating pistachios daily and receiving coaching on healthy habits can improve sleep quality in midlife women aged 45-65 who have poor sleep. Participants will eat either pistachios or potato chips for a month and attend a one-hour coaching session. Researc…

This study tests a new way to treat severe migraines by using a mild electrical current on an artery in the head. Researchers want to see if the procedure is safe and practical for people whose headaches don't get better with standard treatments. About 12 adults with chronic migr…

This study tests if delivering lidocaine (a numbing medicine) and steroids directly into an artery in the scalp can safely relieve the intense headaches that follow a type of brain bleed called subarachnoid hemorrhage. The goal is to reduce pain and the need for strong opioid pai…

This study tests whether taking creatine, a common dietary supplement, can help breast cancer survivors regain strength and endurance faster when combined with a 12-week exercise program. Sixty women who recently finished chemotherapy will be randomly assigned to exercise with or…

This study looks at whether a common dietary fiber called inulin can improve fatigue and thinking problems in people recovering from brain injuries. Researchers will give inulin to 130 adults in neurorehabilitation and track changes in their gut bacteria and symptoms. The goal is…

This study tests whether sildenafil (the drug in Revatio, similar to Viagra) can reduce urine leakage in people with spinal cord injuries. Twenty-four adults who have at least three leaks per week will take either sildenafil or a placebo for four weeks. Researchers will track how…

This study tests a wearable device that uses directional sound to help people with low vision detect obstacles. Fifty participants with normal vision will wear a blindfold and walk a path with obstacles, once with the device and once without. The device emits tones that get loude…

This study tests whether a combination of famotidine (Pepcid) pills and cromolyn sodium lotion can reduce itching from burn scars. 44 adults with itchy burn scars will take either the active combo or a placebo (plus a standard antihistamine) for 6 months. The main goal is to see …

This study looks at why some people lose muscle and strength after weight loss surgery, and why others regain weight. Researchers will track eating habits, grip strength, and body changes in 110 bariatric patients for a year. They will also study genes and metabolism to find fact…

This study tests a new virtual reality (VR) system built into a walking robot to help stroke survivors use their weaker leg more during walking. 30 people (15 stroke survivors and 15 healthy adults) will try a single session of VR-guided walking. The goal is to see if real-time v…

This study tests a new walking training method for people who have had a stroke. It combines treadmill walking with resistance and real-time feedback to help improve leg strength and walking symmetry. The study includes 15 stroke survivors and 15 healthy adults, each attending a …

This study compares two muscle relaxant drugs (rocuronium and cisatracurium) used during general anesthesia in people with chronic kidney disease. Researchers want to see which drug leads to fewer lung problems after surgery. About 490 adults with kidney disease will take part.

This study looks at the gut bacteria of 16 people with advanced solid cancers who are receiving standard immunotherapy. Researchers will analyze stool samples and cognitive function to see if there is a link between the gut microbiome and how well the treatment works. The goal is…

This study looks at how gut bacteria might be linked to memory, thinking, and tiredness in people with cancer. Researchers will collect stool samples and do thinking tests at the start and after 6 months of standard cancer treatment. The goal is to find patterns that could help m…

This study looks at whether a gentle brain stimulation technique called anodal tDCS can improve how people learn stepping movements. Researchers will test this in both healthy adults and chronic stroke survivors. Participants will receive either real stimulation, a sham (fake) st…