The University Of Texas Medical Branch, Galveston

This study aims to see if two doses of the approved 9-valent HPV vaccine provide similar protection against the virus as the standard three-dose schedule for women aged 27-45. Researchers will enroll 618 women who have never received the HPV vaccine and randomly assign them to re…

This study is testing whether the weight-loss medication tirzepatide might slow down the body's aging process. It will involve 90 adults aged 55-70 who are eligible for weight-loss treatment. Participants will either receive a weekly injection of tirzepatide or no drug for 24 wee…

This study is testing whether a 12-week, home-based strength training program guided by telehealth is practical and acceptable for older adults who have both type 2 diabetes and mild cognitive impairment. Researchers want to see if participants can stick with the program and if i…

This study is testing whether involving a person's family can help them better manage type 2 diabetes. Researchers will work with 75 adults from rural Kentucky who have diabetes to create personalized nutrition and exercise plans for their entire household to follow for six month…

This study is testing if a less invasive procedure called middle meningeal artery embolization (MMAE) works as well as traditional open surgery for treating chronic subdural hematomas (slow brain bleeds). Researchers will compare the two treatments in 520 adults with moderate sym…

This study aims to prevent and manage type 2 diabetes in Latino communities by training church members as community health workers. The program helps Spanish-speaking adults access better healthcare and learn about diabetes prevention. Researchers will test whether this church-ba…

This study is testing whether sildenafil, the drug commonly known as Viagra, can help reduce urine leakage in adults with spinal cord injuries. Researchers will enroll 24 participants to take either sildenafil or a placebo pill for four weeks each, tracking how many leakage episo…

This study aims to find a better way to reduce the intense itch that often comes with healed burn scars. Researchers are comparing the standard itch medication (Benadryl) against Benadryl plus two other drugs (Pepcid and a special lotion). The goal is to see if this three-medicin…

This study is testing whether taking a creatine supplement while doing exercise helps breast cancer survivors regain strength, endurance, and muscle mass more quickly after finishing chemotherapy. Researchers will compare 60 breast cancer survivors doing exercise with or without …

This study is testing whether eating pistachios and having a single health education session can improve sleep in women aged 45-65 who have poor sleep quality. For about one month, participants will eat a study snack, meet with a therapist for a session, and track their sleep. Re…

This study aims to find out which of two standard anesthesia drug combinations is safer for patients with chronic kidney disease having surgery. Researchers will compare two sets of drugs used to relax muscles during surgery and then reverse that effect afterward. They want to se…

This early study is testing whether a new procedure that uses gentle electrical stimulation on a specific artery in the head is safe and practical for people with severe, hard-to-treat migraines. Researchers will perform the procedure on 12 adults to see if it can be done without…

This study is testing a new home-based recovery program for adults who have suffered a burn. It compares standard paper exercise instructions to a tech-enhanced program that includes a gamified app, a Fitbit, and weekly virtual coaching. The goal is to see if the tech program hel…

This study is testing whether a therapy called dry needling can help reduce pain and improve daily life for people with long-term low back pain. Researchers will compare three different dry needling session plans in 42 adults. The main goal is to see if the treatment plans are pr…

This study is testing if a medication infusion directly into a brain artery can relieve the severe headaches that follow a type of brain bleed called a subarachnoid hemorrhage. Researchers will give 15 patients either lidocaine, lidocaine with a steroid, or no infusion during a s…

This study is testing if a common dietary fiber called inulin can help people recovering from a brain injury. Researchers want to see if changing the mix of bacteria in the gut can reduce common problems like severe tiredness and trouble thinking. They will give inulin to about 1…

This study aims to understand the connection between gut bacteria and two common, debilitating side effects of cancer treatment: severe fatigue and cognitive problems (often called 'chemo brain'). Researchers will enroll 250 adult cancer patients and analyze their gut bacteria wh…

This study is testing a new wearable device designed to help people with low vision walk more safely. The device uses sound waves to detect obstacles in a person's path and alerts them with tones. Researchers will have 50 participants with normal vision wear special goggles to si…

This study is exploring whether a safe, non-invasive brain stimulation technique can help people learn and improve leg movement skills. It will test this approach in both healthy adults and individuals who have had a stroke at least six months ago. The goal is to understand how b…

This study aims to understand why some people lose muscle and strength after weight loss surgery, and why some regain weight. Researchers will follow 110 patients for a year after surgery, tracking their diet, strength, and body composition. They will also collect gut tissue and …

This study aims to understand how the community of bacteria in a person's gut (the microbiome) might affect how well their cancer responds to immunotherapy drugs. Researchers will compare the gut bacteria of patients whose cancer got worse during treatment to those who were stabl…