Herbal injections at acupuncture points tested against physical therapy for Long-Lasting sciatica
NCT ID NCT07832318
First seen Sep 21, 2026 · Last updated Sep 21, 2026
Summary
Researchers are comparing pharmacopuncture, a treatment that injects herbal medicine at acupuncture points, with physical therapy for adults who have had sciatica leg pain for more than three months. The trial enrolls 92 people aged 19 to 70 with moderate to severe leg pain. Doctors tailor each treatment to the participant and track pain and disability over seven weeks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- pharmacopuncture, a therapy that injects herbal medicine at acupuncture points
- What this could lead to
- If it works, pharmacopuncture could offer a non-surgical option for people whose sciatica pain has lasted months.
- What could go wrong
- This is a small, 92-person study, and results may not apply to everyone. Pharmacopuncture involves injections and carries risks like soreness, bruising, or infection at the injection site.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 92 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Aug 2025
- Expected to finish
-
Dec 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
19 to 70 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
1\. Inclusion Criteria: 1. Persistent sciatica symptoms lasting for more than 3 months. 2. Presence of at least one of the following signs in one or both lower extremities: Muscle weakness / Dermatomal sensory disturbance (hypoesthesia, dysesthesia, tingling, or pain) / Decreased reflexes / Radiating pain aggravated by the Straight Leg Raising (SLR) test 3. Numeric Rating Scale (NRS) score of 4 or higher for leg pain. 4. Aged between 19 and 70 years. 5. Provided written informed consent to participate in the clinical trial. 2\. Exclusion Criteria: 1. Diagnosed with serious conditions that may cause lower limb radiating pain (e.g., spinal metastasis of cancer, acute vertebral fracture, or dislocation). 2. Presence of progressive neurological deficits or severe neurological symptoms. 3. Pain originating from non-spinal soft tissue disorders (e.g., tumors, fibromyalgia, rheumatoid arthritis, gout). 4. Presence of chronic diseases that may interfere with treatment outcomes or interpretation (e.g., stroke, myocardial infarction, renal disease, diabetic neuropathy, dementia, epilepsy). 5. Current use of steroids, immunosuppressants, psychiatric medications, or other drugs that may affect study outcomes. 6. Inappropriate or unsafe conditions for pharmacopuncture, including bleeding disorders, anticoagulant therapy, or severe diabetes with high infection risk. 7. Use of analgesic medications such as Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), or receipt of acupuncture, pharmacopuncture, or physical therapy within the past 7 days. 8. Pregnant, planning to become pregnant, or currently breastfeeding. 9. Within 3 months post-lumbar spine surgery. 10. Participation in another clinical trial within the past month, or planned participation in another clinical trial (including follow-up period) within 6 months from the screening date. 11. Difficulty in completing the informed consent process. 12. Any other condition that the investigator deems inappropriate for participation in the clinical trial.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Chronic pain are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Bucheon Jaseng Hospital of Korean Medicine
COMPLETEDBucheon-si, Gyeonggi-do, South Korea
-
Jaseng Hospital of Korean Medicine
COMPLETEDSeoul, Seoul, South Korea
-
Kyung Hee University Korean Medicine Hospital at Gangdong
COMPLETEDSeongnam-si, Gyeonggi-do, South Korea
-
Kyung Hee University Korean Medicine Hospital at Gangdong
RECRUITINGSeoul, Seoul, South Korea
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- One 2-Hour class may help new mothers manage Post-Cesarean pain
- Zapping deep brain regions to quiet chronic back pain
- Can difficulty naming emotions shape how much tailbone pain you feel?
- Can talk therapy rewire the brain to ease burn Survivors' pain?
- Can a video game teach cancer patients to tame their pain?
- Could a wearable zapper quiet cirrhosis pain without drugs?