Herbal injections at acupuncture points tested against physical therapy for Long-Lasting sciatica

NCT ID NCT07832318

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 21, 2026 · Last updated Sep 21, 2026

Summary

Researchers are comparing pharmacopuncture, a treatment that injects herbal medicine at acupuncture points, with physical therapy for adults who have had sciatica leg pain for more than three months. The trial enrolls 92 people aged 19 to 70 with moderate to severe leg pain. Doctors tailor each treatment to the participant and track pain and disability over seven weeks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
pharmacopuncture, a therapy that injects herbal medicine at acupuncture points
What this could lead to
If it works, pharmacopuncture could offer a non-surgical option for people whose sciatica pain has lasted months.
What could go wrong
This is a small, 92-person study, and results may not apply to everyone. Pharmacopuncture involves injections and carries risks like soreness, bruising, or infection at the injection site.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 92 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

1\. Inclusion Criteria: 1. Persistent sciatica symptoms lasting for more than 3 months. 2. Presence of at least one of the following signs in one or both lower extremities: Muscle weakness / Dermatomal sensory disturbance (hypoesthesia, dysesthesia, tingling, or pain) / Decreased reflexes / Radiating pain aggravated by the Straight Leg Raising (SLR) test 3. Numeric Rating Scale (NRS) score of 4 or higher for leg pain. 4. Aged between 19 and 70 years. 5. Provided written informed consent to participate in the clinical trial. 2\. Exclusion Criteria: 1. Diagnosed with serious conditions that may cause lower limb radiating pain (e.g., spinal metastasis of cancer, acute vertebral fracture, or dislocation). 2. Presence of progressive neurological deficits or severe neurological symptoms. 3. Pain originating from non-spinal soft tissue disorders (e.g., tumors, fibromyalgia, rheumatoid arthritis, gout). 4. Presence of chronic diseases that may interfere with treatment outcomes or interpretation (e.g., stroke, myocardial infarction, renal disease, diabetic neuropathy, dementia, epilepsy). 5. Current use of steroids, immunosuppressants, psychiatric medications, or other drugs that may affect study outcomes. 6. Inappropriate or unsafe conditions for pharmacopuncture, including bleeding disorders, anticoagulant therapy, or severe diabetes with high infection risk. 7. Use of analgesic medications such as Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), or receipt of acupuncture, pharmacopuncture, or physical therapy within the past 7 days. 8. Pregnant, planning to become pregnant, or currently breastfeeding. 9. Within 3 months post-lumbar spine surgery. 10. Participation in another clinical trial within the past month, or planned participation in another clinical trial (including follow-up period) within 6 months from the screening date. 11. Difficulty in completing the informed consent process. 12. Any other condition that the investigator deems inappropriate for participation in the clinical trial.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Bucheon Jaseng Hospital of Korean Medicine

    COMPLETED

    Bucheon-si, Gyeonggi-do, South Korea

  • Jaseng Hospital of Korean Medicine

    COMPLETED

    Seoul, Seoul, South Korea

  • Kyung Hee University Korean Medicine Hospital at Gangdong

    COMPLETED

    Seongnam-si, Gyeonggi-do, South Korea

  • Kyung Hee University Korean Medicine Hospital at Gangdong

    RECRUITING

    Seoul, Seoul, South Korea

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