Can a video game teach cancer patients to tame their pain?
NCT ID NCT07825051
First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time
Summary
Researchers at Dana-Farber Cancer Institute are testing Healing Gardens, a mobile game that delivers pain-focused cognitive behavioral therapy and cancer pain education. The study enrolls 46 adults with advanced solid tumors who have chronic pain related to cancer or its treatment. Participants play the story-based game, which covers pain coping skills, ways to reframe negative thoughts, and safe opioid use. The team measures whether patients find the game acceptable and easy to use, and how many complete the modules.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Healing Gardens, a story-led mobile game that teaches pain coping skills and cancer pain education
- What this could lead to
- If it works, this could offer a low-cost, at-home way for people with advanced cancer to learn pain coping skills and use pain medicines more safely.
- What could go wrong
- This is a small feasibility study, so it mainly tests whether patients find the game usable and acceptable, not whether it actually reduces pain. A game may not appeal to everyone, and any pain relief seen here would need confirmation in larger trials.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 46 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2027
An estimate. Start dates often move.
- Expected to finish
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Jun 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * Patient is diagnosed with a locally advanced or metastatic solid tumor malignancy, either undergoing active treatment or receiving treatment for an advanced cancer or are receiving supportive/palliative care at DFCI * Chronic pain related to cancer or treatment (\> pain score of 4 on a 0-10 scale on average over the past two weeks, Numeric Rating Scale) * Own/use a compatible device (e.g., smartphone, laptop) Exclusion Criteria: * Patients in survivorship: patients who have completed their treatment regimens, are not actively receiving curative or palliative treatment for an advanced cancer, or have a cancer that is in remission * Cognitive impairment that would interfere with study participation, as judged by the treating clinician (e.g. delirium, dementia) * Inability to speak English (the intervention has not yet been translated to other languages) * Enrolled in hospice * Currently hospitalized * Pain primarily related to a recent surgery (within the last 2 weeks) * Conditions that hinder device use (e.g., vision impairment) * We will exclude adults who are unable to consent, individuals who are not yet adults (infants, children, teenagers), pregnant women, and prisoners.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Dana-Farber Cancer Institute at South Shore
Weymouth, Massachusetts, 02190, United States
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