Veterans test 18-Month exercise plan to fight pain and depression

NCT ID NCT05094297

Recruiting now Symptom relief Sponsor: University of Illinois at Chicago Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is testing whether a focused muscle contraction exercise program called the GH Method can improve body composition, physical abilities, and overall well-being in U.S. veterans. Twenty-five veterans with pain, fatigue, or low energy will do 90 exercise sessions over 18 months. Researchers will measure changes in muscle mass, strength, and symptoms like depression and PTSD.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: exercise program (GH Method)
What this could lead to: If it works, this could point toward a simple, drug-free way to ease chronic pain, fatigue, and depression in veterans.
What could go wrong: This is a small, early study with only 25 participants and no comparison group, so results may not apply broadly. The 90-session commitment may also be hard for many to complete.

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Conditions

The condition(s) this trial relates to.

Acute Pain Chronic Pain chronic pain syndrome Depression depressive disorder Fatigue

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE PAIN CHRONIC PAIN DEPRESSION FATIGUE

Contacts and locations

Locations

University of Illinois at Chicago
RECRUITING

Chicago, Illinois, 60612, United States

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