HEART FAILURE

This study tracked 1,200 Japanese adults with chronic heart failure who took JARDIANCE tablets daily for a long time. Researchers monitored side effects like low blood sugar, dehydration, and kidney issues, as well as deaths and hospitalizations. The goal was to see how safe and …

This study looked at whether giving heart failure patients healthy meals or fresh produce boxes for 90 days after leaving the hospital can reduce readmissions and emergency visits. It also tested if making the food support conditional on attending follow-ups or taking medications…

This study tested two ways to pace the left side of the heart in people with severe heart failure. The standard method uses veins on the heart's surface, while the new method paces from inside the heart chamber. Researchers wanted to see if the inside approach offers more pacing …

This study tested the drug sacubitril-valsartan in 60 adults with heart failure and reduced pumping ability. The goal was to see if the drug could lower the risk of major heart problems like heart attack, stroke, or death, and improve the heart's pumping strength. Participants ha…

This study looked at a new way of treating heart valves before they are implanted in people who need a replacement for their aortic or mitral valve. The goal was to make sure the new process is safe and works as well as current methods. Over 700 adults took part, and researchers …

This pilot study tested whether a values-affirmation exercise could help older adults with heart failure stick to their medications during cardiac rehabilitation. 43 participants were randomly assigned to either the values exercise or usual care. The main goals were to see if the…

This study looked at whether a diabetes drug called empagliflozin, plus a breathing machine (CPAP), can improve sleep and heart function in 70 adults with both heart failure and obstructive sleep apnea. Participants were randomly assigned to receive empagliflozin or not, and all …

This study looked at the safety of the heart failure drug sacubitril/valsartan in Japanese children under 18 who had already finished a previous study. The goal was to collect more safety information and give these children access to the drug until a child-friendly version is ava…

This study tested a new device called the DuoCor Ventricular Assist System in 8 adults with severe heart failure. The device is implanted to help the heart pump blood. The main goal was to see if patients survived for 3 months after implantation, either with the device, after a h…

This study looked at 411 people with both heart failure and atrial fibrillation (a fast, irregular heartbeat). It compared two approaches: using a catheter to burn small areas in the heart to restore normal rhythm, versus simply controlling the heart rate with medication. The goa…

This early-phase study tested a new treatment called CAR-DC in 8 adults with end-stage dilated cardiomyopathy, a condition where the heart becomes enlarged and weak. The therapy uses specially engineered immune cells to target a protein (FAP) linked to scar tissue in the heart. T…

This study tested a program called PRADO that helps heart failure patients transition from hospital to home care. It included 404 adults who had been hospitalized for heart failure. The program aimed to reduce hospital readmissions and deaths by coordinating doctors, nurses, and …

This study tested new strategies to help doctors prescribe proven heart failure medications to more patients. Over 4,300 adults with heart failure and reduced pumping ability took part. The goal was to increase use of these drugs to lower death rates and prevent hospital stays.

This study tested a program to help people with heart disease in India get better care. The program used health workers, text messages about healthy living, and a computer tool to help doctors make decisions. 410 adults with heart disease took part to see if the program improved …

This study looked at whether a clinic run by a heart failure nurse could help patients with an implantable cardioverter defibrillator (ICD) get the right medications. The goal was to improve heart function and reduce hospital visits. The study included 29 adults with heart failur…

This study tested a program for people with heart failure that combines remote monitoring (tracking symptoms and weight at home) with nurse education and a hospital check-up. The goal was to see if this approach could reduce hospital stays and deaths. The study included 504 older…

This study tested an investigational drug called AZD3427 in 260 adults with heart failure and a related lung condition called pulmonary hypertension (Group 2). The goal was to see if the drug could lower blood pressure in the lungs' arteries after 24 weeks of treatment. Participa…

This study tested whether daily bedside ultrasound helps doctors better adjust treatment for people hospitalized with acute heart failure. The goal was to reduce the number of patients readmitted within 30 days. The study involved 250 adults with heart failure and low heart funct…

This study tested a new drug called tovinontrine in 303 adults with chronic heart failure (a condition where the heart doesn't pump as well as it should). The goal was to see if the drug could lower a key marker of heart strain (NT-proBNP) compared to a placebo. The trial has com…

This study tested a procedure called pulmonary artery denervation (PADN) in 30 adults with both heart failure and high blood pressure in the lungs. Participants were already on standard heart failure medications and were followed for one year after the procedure. The main goal wa…

This study tested whether a low dose of digoxin, a very old and cheap heart drug, can help people with chronic heart failure. About 982 adults with heart failure and reduced pumping function took either digoxin or a placebo. The goal was to see if digoxin could reduce hospital st…

This study tested a new way to help heart failure patients with weak hearts and implanted defibrillators get the best medications. Over 2,400 patients were involved. The goal was to improve medication use through a nurse-led program, aiming to reduce hospital visits and improve q…

This study tested a newer pacing method (left bundle branch area pacing) against the standard method (right ventricular pacing) in 486 adults with heart block. The goal was to see if the newer method better preserves heart function and reduces risks like death, heart failure hosp…

This study looked at whether a daily pill (SGLT2 inhibitor, like dapagliflozin or empagliflozin) can help people without diabetes who had a heart attack and a stent placed. The goal was to see if the drug could lower the chance of being hospitalized for heart failure, having anot…

This study looked at whether empagliflozin, a diabetes drug, can improve heart structure in people with heart failure who do not have diabetes. 50 patients with preserved ejection fraction (a type of heart failure where the heart pumps normally but is stiff) took part. Researcher…

This study tested two drugs—hydralazine-ISDN and metformin—in 1100 people with chronic heart failure and reduced heart function. The goal was to see if these drugs could lower the risk of death or hospitalization due to worsening heart failure. Participants took either the drugs …

This pilot study tested whether a community health worker (CHW) program could help heart failure patients in rural Haiti stay connected to care. Thirty adult patients hospitalized with heart failure received home visits and support from trained CHWs. The study measured how accept…

This study looked at whether giving hospital-level care to acutely ill adults in their own homes in rural areas works well. 160 people with various conditions like infections, heart failure, or COPD took part. The main goal was to see if this approach could lower costs and keep p…

This study tested a new medicine called tovinontrine in 557 adults with chronic heart failure and reduced pumping ability. The goal was to see if it safely lowers a key heart stress marker (NT-proBNP) compared to a placebo. Participants took the drug or placebo for 12 weeks, and …

This early-stage study tested a new medicine called CDR132L in 28 people with stable heart failure caused by blocked arteries. The main goal was to check if the drug is safe and how the body processes it. Participants received either the drug or a placebo, and researchers monitor…

This early study tested a single injection of a new RNA-based medicine (HM2002) given directly into the heart muscle during bypass surgery in 3 people with heart failure. The main goal was to check safety and tolerability. Researchers also looked for signs of improved blood flow …

This study looked at 180 people with heart failure and a leaky mitral valve. Researchers compared taking one heart drug (ARNI) alone versus taking it with another drug (SGLT2 inhibitor). They measured changes in heart function and valve leakage to see which approach worked better…

This study tested whether a small wearable sensor, combined with a computer model, could detect early signs of worsening heart failure in veterans. Half of the 176 participants were monitored remotely, and their care teams were alerted when the system predicted a flare-up. The go…

This study looked at whether a procedure called cryoballoon ablation (freezing the veins near the heart) can safely and effectively treat atrial fibrillation (an irregular heartbeat) in people who also have severe heart failure. About 1,420 adults with symptoms and a weak heart p…

This study tested whether doxycycline, an antibiotic also used for gum disease, could prevent heart damage after a heart attack. 174 adults who had a severe heart attack took either doxycycline or a placebo twice a day for one week. Researchers used MRI scans three months later t…

This study tested whether providing heart failure patients with pre-made, heart-healthy meals made from traditional Navajo foods could reduce hospital visits and ER trips. Over 200 adults received either these special meals or their usual care for 60 days. The goal was to see if …

This study looked at whether a clinic focused on guideline-recommended heart failure medications helps patients get more of the right drugs. Researchers compared 342 patients who went to the special clinic to similar patients getting usual care. The goal was to see if more patien…

This study tested whether a more detailed remote monitoring system could reduce deaths or hospital stays for heart failure patients who have a special pacemaker (CRT). Over 650 adults were followed for 27 months. The goal was to see if comprehensive monitoring works better than s…

This study tested a device called Barostim NEO that uses mild electrical pulses to activate a natural reflex that helps control blood pressure and heart function. It involved over 1,000 people with advanced heart failure who were already on standard medications. The goal was to s…

This study looked at a new way to pace the heart in 150 people with heart failure and a specific type of heart block (left bundle branch block). Instead of the standard pacing method, doctors tried pacing directly at the heart's natural electrical system. The goal was to see if t…

This study tested a special feature in pacemakers that automatically adjusts timing and pacing to help the heart pump better. 198 people with heart failure and a wide QRS received the device and were followed for 12 months. The goal was to see if the feature improved symptoms, re…

This study looked at whether doing cardiac rehab at home, or a mix of home and clinic visits, is as effective as going to the clinic for rehab. 206 adults with heart conditions took part. The goal was to see if remote options could improve access and outcomes.

This early-phase study tested whether giving the heart medication carvedilol to breast cancer patients at high risk for heart problems could safely protect their hearts during chemotherapy with doxorubicin and/or trastuzumab. 68 women with stage I-III breast cancer participated. …

This study tested a drug called sacubitril/valsartan against an older drug, enalapril, in 922 adults with heart failure caused by Chagas disease. The goal was to see if the newer drug could reduce heart-related deaths, hospitalizations, and improve a key heart stress marker (NT-p…

This study tested whether a single daily pill containing three heart failure medications could help low-income and minority patients better manage their condition. 212 adults with heart failure and reduced pumping function took part. The goal was to see if this simple approach im…

This study tested whether a specialized clinic (GDMT Clinic) helps heart failure patients receive more of the recommended medications compared to usual care. About 300 adults with heart failure, including those with new diagnoses, took part over 12 weeks. The goal was to see if t…

This study compared two water pills (torsemide and furosemide) in nearly 3,000 people hospitalized with heart failure. The goal was to see if one pill was better at preventing death or the need for another hospital stay over 12 months. Both medicines are already used to manage he…

This study looked at health records of over 1,200 people with heart failure to compare two types of medication: sacubitril/valsartan versus ACE inhibitors or ARBs. The goal was to see which treatment better reduced the risk of death from heart problems or hospitalization due to h…

This study tested a nurse-led smartphone app to help heart failure patients manage their health at home after leaving the hospital. 104 patients were split into two groups: one got the app plus regular care, the other got regular care alone. The app provided medication reminders,…

This study tested a remote monitoring system (Seerlinq HeartCore) in 330 adults with chronic heart failure. The system tracked health data and guided treatment changes to prevent worsening symptoms. The goal was to see if this approach could lower the number of hospitalizations a…

This study tested whether probenecid, a medicine usually used for gout, can help veterans with a type of heart failure called heart failure with reduced ejection fraction (HFrEF). About 99 veterans took probenecid twice a day for 180 days. Researchers measured changes in heart fu…

This study looked at whether empagliflozin, a medicine already used for diabetes and heart conditions, can help improve the heart's shape and pumping ability in people with diabetes who had a major heart attack. Two hundred patients took either a 10 mg or 25 mg dose and were moni…

This study tested a home-based digital health program for 104 adults with heart failure. The program included smartphone tools, remote monitoring, and therapy sessions to help patients manage their condition after leaving the hospital. Researchers measured improvements in heart f…

This study tested a web application designed to help people with heart failure optimize their medications. 225 adults with heart failure and reduced ejection fraction participated. The app analyzed patient data and provided personalized medication recommendations in plain languag…

This study looked at whether closer collaboration between doctors and pharmacists could reduce the number of heart failure patients who need to be readmitted to the hospital within three months. Researchers compared standard care to a more coordinated approach involving pharmacis…

This study tested whether a structured plan for giving diuretics (water pills) to patients hospitalized with worsening chronic heart failure is safer and more effective than usual care. About 299 adults took part. The goal was to see if the protocol helped patients lose excess fl…

This study looked at two different types of support for heart failure patients after they leave the hospital. One group got a phone call from a care coordinator, while the other had access to a community paramedic who could visit their home and connect them with a doctor via vide…

This study tested two remote care approaches to help heart failure patients get the right medications. Over 500 adults with heart failure took part, and the goal was to see if these strategies could increase use of recommended drugs. The focus was on optimizing existing treatment…

This study tested whether the drug henagliflozin, taken for 6 months after a heart attack, can reduce the size of heart muscle damage and improve heart function. 248 adults who had a specific type of heart attack (STEMI) and underwent a procedure to open blocked arteries particip…

This study looked at how well the drug sacubitril/valsartan works in African American patients with heart failure. Over 6,500 participants were followed for at least three months. The goal was to see if the drug reduces deaths and hospital stays, since earlier research suggested …

This study tested a technology-based program that involves family members to help people with advanced heart failure take better care of themselves after leaving the hospital. The program used a smartphone app to support self-care and improve quality of life. 270 patients in Hong…

This study tested a new way to screen for heart failure during regular checkups with a general practitioner. 216 adults aged 65 and older without known heart problems took part. Doctors used a questionnaire, a blood test, and a heart ultrasound to find early signs of the disease.…

This study tested a new blood test called HEARTBiT that may detect when the body is rejecting a transplanted heart. Currently, patients need many invasive heart biopsies to check for rejection. The test looks at 9 RNA markers in the blood and could be faster, cheaper, and less pa…

This study looked at whether measuring a substance called ST2 in the blood can help doctors better diagnose and manage heart failure. Researchers followed 123 patients hospitalized for heart failure to see if using ST2 levels could reduce the number of patients readmitted within …

This study tested a new blood test (called BNP) for heart failure on 1,361 people. The goal was to see if the test correctly identifies those with heart failure and those without. The test was done using a special machine, and results were compared to another device to make sure …

This study tested whether a smartwatch can detect heart failure by tracking body signals like heart rate and movement, and recording voice patterns. Researchers compared 56 people with and without heart failure during physical tasks and daily life. The goal is to find patterns th…

This study tested a special ultrasound technique called ShearWave Elastography to measure liver stiffness as a way to assess liver disease without a needle biopsy. Over 1,200 adults with chronic liver disease, liver transplants, or heart failure had a quick scan during their regu…

This study tested a new wearable device called Seerlinq HeartCore that uses light sensors and artificial intelligence to monitor heart pressure in people with heart failure. The goal was to see if it can accurately measure heart pressure without the need for invasive procedures. …

This study aimed to create better diagnostic tools for heart failure with preserved ejection fraction (HFpEF), a type of heart failure that is difficult to diagnose, especially in older adults with conditions like high blood pressure or obesity. Researchers tested a combination o…

This study looked at whether a heart-healthy DASH diet (low salt, high quality) could prevent heart failure in 71 Veterans who had high blood pressure and metabolic syndrome (a cluster of conditions like obesity and abnormal cholesterol). Participants followed the diet and resear…

This study tested whether nebivolol, a beta-blocker, could prevent heart muscle weakness in boys aged 10–15 with Duchenne muscular dystrophy. Participants had normal heart function at the start and were randomly assigned to receive nebivolol or a placebo. The trial found that neb…

This study tested whether heart failure patients could do cardiac rehabilitation at home using a tablet app instead of going to the hospital. Thirty stable heart failure patients were split into two groups: one did rehab at home with remote monitoring, the other at the hospital. …

This study tested whether taking a probiotic called Lactobacillus plantarum 299v for 12 weeks could improve exercise capacity and blood vessel function in people with chronic heart failure. Ten adults with heart failure and signs of inflammation took either the probiotic or a pla…

This study looked at whether changing the order of exercises during a workout can improve heart function in men with chronic heart failure. Sixty men aged 55-65 with mild to moderate heart failure took part. Researchers measured heart pumping ability and quality of life before an…

This study tested a sleep improvement program delivered through WhatsApp for people with heart failure. 28 participants received personalized sleep tips and reminders based on their readiness to change. The goal was to see if this approach could improve sleep quality, sleep habit…

This study looked at whether a cardiac rehab program with moderate or high-intensity exercise can help heart failure patients who have muscle weakness and trouble breathing. 22 adults took part. The goal was to see if exercise improves aerobic capacity, symptoms, and quality of l…

This study tested whether a single dose of a ketone drink could improve heart function in 20 people with stable heart failure. Participants had cardiac MRI scans after taking the ketone supplement or a carbohydrate placebo. The goal was to see if the supplement could help the hea…

This study tested a program for caregivers of people with advanced heart failure. The program helps caregivers build on their strengths, find purpose, and set goals for a healthier lifestyle. Researchers hope it will improve caregivers' quality of life, reduce their sense of burd…

This early-stage study tested a new patch that delivers the water pill furosemide under the skin to 20 hospitalized heart failure patients. The main goal was to see if the patch is safe, tolerable, and works well. Researchers measured side effects, pain at the patch site, and how…

This study tested whether an extended-release form of the water pill torsemide works better than the standard version for heart failure patients who also have overactive bladder symptoms. 24 adults aged 50 and older with chronic heart failure took each version for four weeks and …

This study tested whether a 12-week home exercise program is practical for people with chronic heart failure who were recently hospitalized. Thirty participants received in-person training and follow-up visits. The goal was to see how many completed the program and whether it imp…

This study tested a program that encourages doctors to offer specialized home-based palliative care to people with serious heart failure. The goal was to see if this approach reduces time spent in the hospital and lowers healthcare costs. Over 700 patients took part, and the prog…

This study tested whether high-intensity interval training (HIIT) reduces harmful nerve activity more than moderate continuous training in 35 people with heart failure. Researchers measured nerve signals, blood vessel function, and muscle health. The goal was to see which exercis…

This study tested whether a long-acting version of the water pill torsemide helps people with heart failure get rid of more salt after lunch compared to the standard version. Twenty adults with stable heart failure took both types of pills on different days to compare their effec…

This study looked at whether the drug vericiguat can improve blood vessel function, reduce inflammation, and help people with heart failure feel better. Twenty-six adults with heart failure and reduced pumping ability took part. Researchers measured changes in blood vessel health…

This study tested a 12-week online program that combines gentle movement, breathing exercises, and coping skills for adults with chronic conditions like heart failure, liver disease, or cancer. The goal was to see if it could reduce anxiety and depression. Over 800 people took pa…

This study tested whether animated nutrition videos could help heart failure patients improve their eating habits, reduce symptoms, and feel better overall. 70 adults aged 45-60 with moderate heart failure were split into two groups: one watched the videos, the other got standard…

This study tested a web-based program called 'Heart to Heart' that helps heart failure patients, their family caregivers, and nurses work together better. 150 adults with heart failure, their caregivers, and nurses took part. The program aims to improve quality of life and commun…

This study tested a web-based support program for people caring for someone with heart failure. The program aimed to help caregivers feel more prepared and supported in their role. 202 caregivers participated, with some receiving the online program and others getting standard car…

This study gave 60 people with heart failure free, medically tailored meals for 12 weeks to see if it would improve their diet quality. The main goal was to measure how healthy their eating became using a standard diet score. Researchers also checked how satisfied participants we…

This study tested whether people with heart failure could leave the hospital earlier by receiving a special form of the water pill furosemide at home instead of staying in the hospital for IV treatment. 172 adults took part, and researchers measured how many days they were alive …

This study tested a 6-month program called ENABLE for heart failure patients and their caregivers in Singapore. The program provides education, support, and advice to help manage the condition. Researchers wanted to see if the program was easy to use and if it could improve quali…

This study tested whether a personalized exercise program, guided by an Apple Watch, can improve fitness and quality of life in people with dilated cardiomyopathy, a condition that weakens the heart. 300 participants were followed for 13 months. The main goal was to see if their …

This study tested a 12-week program for heart failure patients and their family caregivers. The program focused on improving their relationship, emotional strength, and quality of life. 192 patient-caregiver pairs took part, with some receiving the program and others getting usua…

This study looked at whether special lymphatic exercises can reduce fluid overload symptoms like shortness of breath, leg swelling, and fatigue in people with heart failure. 80 participants were split into two groups: one did the exercises for 4 weeks, the other just monitored th…

This study looked at information from over 2,400 people with heart failure, both in the hospital and during follow-up visits. The goal was to improve how doctors treat heart failure by grouping patients based on their risk of future health problems. No new drugs or treatments wer…

This study looked at how beta-blocker medicines improve heart function in people with heart failure. Researchers measured changes in the heart's ability to contract and pump blood. The goal was to understand the underlying mechanisms, not to test a new treatment. 55 adults with n…

This early-stage study tested a new drug called THRV-1268 in 16 healthy obese adults to see if it is safe and how the body handles it. Participants received a single dose of the drug or a placebo. The goal was to check for side effects and measure how the drug moves through the b…

This study looked at whether common heart failure medications are linked to falls in people aged 65 and older. Researchers analyzed a global safety database of 100,000 reports to find patterns. The goal was to identify which drugs might pose a higher fall risk, not to test a new …

This study looked at whether signs of heart failure can be found in fluid just under the skin, instead of in blood. Twenty heart failure patients had their skin fluid tested during exercise. The goal was to see if this painless method could help predict when the disease gets wors…

This study examined how COVID-19 lockdowns changed health behaviors and medication use in over 1,300 people with chronic conditions like heart disease, multiple sclerosis, and macular degeneration. Researchers found that isolation, stress, and difficulty accessing care led to cha…

This study tested whether motion-capture tools (sensors and cameras) can objectively measure physical function in elderly people with heart failure. Researchers analyzed movement during simple tasks to develop a new way to classify patients by their functional ability. The goal w…

This study tested whether an augmented reality (AR) tool, accessed via a QR code on a smartphone, could help heart patients better understand their discharge instructions. Over 300 adults hospitalized for heart attack, heart failure, atrial fibrillation, or pacemaker implantation…

This study tested whether a mobile app that gives visual feedback and motivational messages can help older adults (60+) with conditions like COPD, heart failure, or Parkinson's become more active during their hospital stay and for three months after going home. Researchers tracke…

This study gathered information from 254 Mexican adults with heart failure and reduced pumping ability. Researchers tracked their medical treatments, device use, and outcomes to identify common care patterns and barriers. The goal was to better understand real-world heart failure…

This study tested an automatic alert in electronic health records to remind doctors to prescribe recommended heart failure medications. Over 1,100 patients with weak heart pumping function took part across four health systems. The goal was to see if the alert increased prescripti…

This study examined how often adults with chronic heart failure were prescribed SGLT2 inhibitors (a type of medication) when they joined a nationwide remote monitoring program in France between 2021 and 2024. Researchers looked at trends over time and factors like patient charact…

This study checked if special heart devices (called SureScan CIEDs) are safe during powerful 3.0T MRI scans. 64 adults with these devices got an MRI and were followed for one month. The goal was to see if any serious problems happened because of the MRI. The results help doctors …

This study tested a new digital strategy to help heart failure patients start a helpful medicine (SGLT-2 inhibitor) more quickly. Over 5,900 adults in Denmark with heart failure were invited by official digital letters to check if they were eligible. The goal was to see if this a…

This study tested a program to improve heart failure care for Black and Latinx patients who are often treated on general medicine floors instead of cardiology. The program included better treatment plans, cardiology checkups, and help with transportation. 79 patients took part to…

This study tested a new way to give the water pill furosemide—as a single shot under the skin—compared to the standard method through an IV line. Twenty-one healthy adults aged 45 to 80 took part to see how well the body absorbs the drug and how it affects urine output. The goal …

This study looked at 502 people with heart failure who were getting an implantable cardioverter-defibrillator (ICD) to prevent sudden cardiac death. Researchers used a special MRI scan to see if heart muscle scarring could predict who would later need a shock from their device. T…

This study looked at whether having heart failure patients fill out a short, 12-question survey about their symptoms and quality of life at each clinic visit helps doctors provide better care. Over 1,200 adults from a Stanford heart failure clinic took part. Some started the surv…

This study tested whether a portable ultrasound device can accurately measure muscle loss in people with heart failure, compared to the standard X-ray method. Researchers enrolled 48 participants, including healthy volunteers and heart failure patients. The goal was to see if ult…

This study looked at medical records of 4,000 heart failure patients to see if combining routine blood tests (like NT-proBNP) with heart scan results (like fat density around the heart) could better predict who might die within a year. The goal is to improve personalized risk ass…

This study tested whether gentle reminders sent to doctors could increase the use of two types of life-saving heart failure medications. The study involved 81 doctors and other clinicians at a VA hospital. The goal was to see if these "nudges" helped more veterans get the right p…

This study checked how well hospitals in Germany follow recommended treatments for people with heart failure after a serious episode. About 900 patients took part, and researchers looked at whether care matched official guidelines. The goal was to understand where care is strong …

This study looked at ways to protect the right side of the heart after patients receive a mechanical pump (LVAD) for heart failure. Twenty adults who had LVAD surgery were monitored closely for several days. The goal was to find better methods to prevent right heart problems afte…

This study aimed to translate a common heart failure quality-of-life questionnaire into Urdu and check if it works properly. Researchers enrolled 210 heart failure patients in Pakistan. The goal was to create a reliable tool for doctors to measure how heart failure affects daily …

This study looked at 32 adults who had heart surgery to see if a liver ultrasound could help find right-sided heart problems. Right heart issues are common after surgery and can lead to kidney or liver failure. The researchers measured blood flow in the liver and compared it to s…

This study looked at over 30,000 adults hospitalized in Maryland to understand why some patients wait in the emergency room after being admitted (called boarding) and how that affects costs and care. Researchers analyzed existing medical records to find patterns and financial imp…

This study followed 257 adults with heart failure who were prescribed dapagliflozin. Researchers wanted to see how patients used the medication in everyday life and how their quality of life changed. The goal was to gather real-world information, not to test a new treatment.

This study looked at how fluid buildup (congestion) changes in adults hospitalized for heart failure. Researchers tracked 49 patients using exams, blood tests, and ultrasound to understand the process. Participants were followed for one year to see how many were readmitted or die…

This study checked how easy and acceptable the P-STEP mobile app is for people with chronic conditions like asthma, COPD, heart disease, or type 2 diabetes. 178 adults in Leicester, UK, used the app for 12 weeks. The goal was to see if the app is user-friendly and helpful for man…

This study looked at how heart failure patients' own reports of their health can signal changes in their condition. Over 1,000 adults participated by completing surveys and some gave blood samples. The goal was to learn how patient experiences and biology relate to disease progre…

This study looked at whether using a heart ultrasound during pacemaker implantation helps doctors find the right spot for the wire. 33 adults with heart failure who needed a pacemaker took part. The goal was to see if this approach shortens procedure time and reduces X-ray exposu…

This study looked at two methods for assigning care coordinators to older adults (65+) with heart disease or risk factors like diabetes and high blood pressure. The goal was to see which approach better prevented emergency room visits and hospitalizations. Researchers compared as…

This completed study surveyed 608 heart and kidney specialists to understand their awareness and use of a blood test called hsCRP, which measures inflammation. The goal was to learn what doctors think about inflammation's role in managing atherosclerotic cardiovascular disease, c…

This study looked at 18 heart failure patients with a specific electrical issue called left bundle branch block. Researchers mapped the best spots in the heart to place a pacemaker lead to fix the electrical problem. The goal was to understand where pacing works best, not to test…

This study tested new MRI methods to better detect bleeding inside heart muscle after a heart attack. Researchers studied 14 adults who had a heart attack to see if these scans could map the bleeding more clearly. The goal is to help doctors identify patients at higher risk for h…

This study looked at 30 children with heart failure to understand how their breathing and sleep are affected. Researchers measured the effort it takes for these children to breathe and checked their sleep quality. They also tested whether using a breathing mask (CPAP) while awake…

This study looked at data from 372 patients who were part of a home hospital program. Researchers used a computer program (machine learning) to see if it could predict which patients would need to be readmitted to the hospital within 30 days. The goal was to learn if this approac…

This study tested a device that measures foot volume changes in people with heart failure. The goal was to see if it helps doctors adjust diuretic (water pill) treatment at home and detect early signs of fluid buildup before a hospital visit. 23 patients participated, and the stu…

This study tested whether a 'teach-back' education session—where patients repeat discharge instructions in their own words—helps heart failure patients better manage their condition at home. Researchers enrolled 57 adults hospitalized with heart failure and measured changes in se…

This study looked at whether watching videos or reading text helps people with heart failure learn more about their condition. 130 adults with heart failure took part. They were randomly assigned to watch videos or read text about heart failure medications and self-care, and then…

This study collected information from 383 people with slow heartbeats or heart failure who received a special type of pacemaker called conduction system pacing. The goal was to see how well this pacing method works in everyday medical practice around the world. Researchers tracke…

This study used artificial intelligence to analyze electrocardiograms (ECGs) from nearly 287,000 adults in China and the United States. The goal was to see if the AI could predict who might develop a type of heart failure (with reduced pumping ability) up to five years before sym…

This study involved 100 patients with serious illnesses like cancer, heart failure, COPD, or ALS who were receiving palliative care. Researchers used a questionnaire to find out patients' spiritual needs and then provided specialized spiritual care to address them. The goal was t…

This pilot study tested whether a structured exercise program is practical and safe for young cancer survivors (ages 18-45) who are at risk for heart problems due to past treatments. The study enrolled 30 participants and focused on measuring recruitment, safety, and how well par…

This study tested whether a program combining nurse coaching calls and home monitoring of vital signs is practical and acceptable for older adults with heart failure. 46 patients participated after a hospital stay. The goal was to see if patients would stick with the program and …

This study looked at 58 adults with heart failure to find out why they come back to the emergency room within 30 days of being discharged. The goal was to identify key factors that lead to early readmission and suggest ways to improve follow-up care. The research did not test a n…

This study looked at how the heart failure drug Entresto lowers blood pressure. Researchers tested 46 people with heart failure to see if a nausea drug called aprepitant changes how Entresto works. The goal was to understand the body's response, not to test a new treatment.

This study looked at whether an AI-enhanced electrocardiogram (ECG) can predict heart problems caused by cancer treatments like chemotherapy and immunotherapy. Over 31,000 adults who had an ECG before starting cancer therapy were included. The goal was to see if this simple, low-…

This completed study used advanced MRI scans to look at heart structure and function in 276 adults with chronic kidney disease (stages 3-5). The goal was to identify different types of heart damage linked to kidney failure and dialysis, and to see which patterns lead to worse out…

This study looked at whether using cardiac MRI (a type of heart scan without radiation) can make it safer and more accurate to check children with heart failure, heart muscle disease, or who have had a heart transplant. Researchers compared MRI results with standard biopsy and X-…

This study looked at whether a computer program could predict when patients being treated at home might suddenly get worse. Researchers used data from 526 patients to train and test the program. The goal was to see if the program could alert doctors early, helping prevent serious…

This study looked at 158 heart failure patients aged 18-65 to understand how their health literacy and stress levels relate to their quality of life. Researchers used questionnaires and machine learning to find patterns. The goal was to help nurses better assess and support patie…

This study checked if an Apple Watch can reliably measure heart and fitness data in people with heart conditions and athletes. Fifty adults wore the watch while doing treadmill tests and a 6-minute walk. The goal was to see if smartwatch readings match those from hospital-grade e…

This study compared two types of cameras (a newer CZT camera and a standard Anger camera) for taking images of the heart's nerve function in people with stable heart failure. The goal was to see if the newer camera works as well as the standard one. 45 adults with heart failure a…

This study looked at whether sending a reminder to a patient's primary doctor about a high BNP blood test result could help find undiagnosed heart failure. Researchers included 115 patients with high BNP levels but no recent heart imaging. The goal was to see if the alert led to …

This study looked at how HeartInsight, a remote monitoring tool built into certain pacemakers, helps doctors spot early signs of worsening heart failure. About 100 heart failure patients with BIOTRONIK CRT-D devices were followed to see how doctors used the alerts and what action…

This study looked at whether orienteering (navigating a course) is as good as regular walking for heart rehab. 40 adults with heart disease participated. Researchers measured heart rate and enjoyment during both activities. The goal was to see if orienteering offers similar heart…

This study looked at 623 adults with heart failure or high blood pressure in the lungs to see how well different heart pressure tests work. Doctors compared simple ultrasound tests with more invasive catheter measurements. The goal was to find which tests best show if the heart's…

This early-phase study investigated whether raising ketone levels in the blood could improve heart function in people with both type 2 diabetes and heart failure. Researchers gave 41 participants infusions of a ketone substance at different doses and used heart scans (MRI and PET…