Heart failure patients get RNA boost during bypass in first human test

NCT ID NCT06621576

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early study tested a single injection of HM2002, a circular RNA, given directly into the heart muscle during bypass surgery. Only 3 people with heart failure took part. The main goal was to check safety, not to prove it works. The study is complete, but results are not yet available.

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Conditions

The condition(s) this trial relates to.

congestive heart failure coronary artery disorder heart failure myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ruijin Hospital Shanghai Jiao Tong University School of Medicine

    Shanghai, Shanghai Municipality, 200025, China