New injection shows promise for heart failure patients
NCT ID NCT06264310
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a new drug called R2R01 in 33 people with worsening heart failure. Participants received either R2R01 or a placebo alongside their usual treatments. The goal was to see if the drug is safe and helps reduce fluid buildup in the heart.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
R2R01 (a relaxin agonist given as an injection)
What this could lead to
If successful, this could lead to a new add-on treatment to help manage worsening heart failure and reduce hospitalizations.
What could go wrong
This is an early Phase 2 trial with only 33 participants, so results may not apply widely. The drug may not show clear benefit or could have side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Amavita Clinical Research
Miami, Florida, 33137, United States
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C&R Research
Fort Meyers, Florida, 33919, United States
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C&R Research
Hialeah, Florida, 33013, United States
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Encore Clinical Research
Inverness, Florida, 34452, United States
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Encore Clinical Research
Jacksonville, Florida, 32216, United States
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J&S Studies
College Station, Texas, 77845, United States
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Lake Country
Eatonton, Georgia, 31024, United States
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Thomas Hospital
Fairhope, Alabama, 36532, United States