HEART FAILURE
Clinical trials for HEART FAILURE explained in plain language.
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Massive study tests which diabetes pill best protects heart failure patients
Disease control OngoingThis study compares two diabetes medications, oral semaglutide and sitagliptin, in over 25,000 adults with type 2 diabetes and heart failure with preserved ejection fraction. The goal is to see which drug better prevents heart failure worsening, hospitalizations, or death. Resear…
Matched conditions: HEART FAILURE
Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated May 17, 2026 00:53 UTC
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Heart failure device lead under Long-Term watch in 1,092 patients
Disease control OngoingThis study looks at how safe and reliable a specific heart device lead (Attain Stability Quad) is over 5 years in people with heart failure. About 1,092 patients who already have or will get this lead are being followed. The goal is to make sure the lead works well without causin…
Matched conditions: HEART FAILURE
Sponsor: Medtronic • Aim: Disease control
Last updated May 17, 2026 00:53 UTC
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New heart valve replacement could help thousands with leaky valve
Disease control OngoingThis study tests a new device called the Edwards EVOQUE system to replace the tricuspid valve in people with severe leakage. The goal is to see if it safely reduces leakage and improves symptoms like shortness of breath and fatigue. About 864 adults with severe tricuspid regurgit…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated May 17, 2026 00:52 UTC
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New heart pump aims to keep patients stable during risky procedures
Disease control OngoingThis study tests a temporary heart pump (Supira System) in 71 people with heart disease who need a high-risk procedure to open blocked arteries. The pump is designed to keep blood pressure stable during the procedure. The goal is to see if the device is safe and works as intended…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Supira Medical • Aim: Disease control
Last updated May 17, 2026 00:52 UTC
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Heart repair breakthrough? stem cells injected during bypass aim to restore damaged muscle
Disease control OngoingThis study tests whether injecting lab-grown heart muscle cells into the heart during bypass surgery can help people with severe chronic heart failure. About 36 adults with damaged heart tissue will receive the cells and be monitored for safety and heart function improvements. Th…
Matched conditions: HEART FAILURE
Phase: PHASE1, PHASE2 • Sponsor: HELP Therapeutics Co., Ltd. • Aim: Disease control
Last updated May 17, 2026 00:51 UTC
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Tiny heart sensor could cut hospital stays for heart failure patients
Disease control OngoingThis study tests if a small sensor implanted in the lung artery can help doctors better manage heart failure. 554 adults with advanced heart failure and a recent hospital stay are taking part. The sensor sends daily pressure readings to the care team, who adjust medications as ne…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: IHF GmbH - Institut für Herzinfarktforschung • Aim: Disease control
Last updated May 17, 2026 00:50 UTC
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New heart shunt device aims to ease heart failure symptoms
Disease control OngoingThis study looks at a device called the InterAtrial Shunt that creates a small opening between the upper chambers of the heart to lower pressure. It is for people with heart failure and aims to improve symptoms and quality of life. The study will follow 500 patients in Germany to…
Matched conditions: HEART FAILURE
Sponsor: Corvia Medical • Aim: Disease control
Last updated May 17, 2026 00:49 UTC
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Heart failure drug trial halted before it began
Disease control TerminatedThis study aimed to test an experimental drug called OPC-131461 in people hospitalized with worsening heart failure who still had fluid buildup after initial treatment. The goal was to see if the drug could improve a key heart stress marker over 30 days compared to a placebo. How…
Matched conditions: HEART FAILURE
Phase: PHASE2 • Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc. • Aim: Disease control
Last updated May 17, 2026 00:49 UTC
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New heart pump could offer hope for severe heart failure patients
Disease control TerminatedThis study compares a new heart pump (EVAHEART2) to a standard one in 399 adults with severe heart failure. The goal is to see if the new pump helps people survive until a heart transplant or recover without major complications like stroke. Participants must have very weak hearts…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Evaheart, Inc. • Aim: Disease control
Last updated May 17, 2026 00:48 UTC
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Can a diabetes drug boost heart function in non-diabetic patients?
Disease control OngoingThis study tests whether empagliflozin, a drug typically used for diabetes, can help people with hypertrophic cardiomyopathy (a thickened heart muscle) who do not have diabetes. Over 12 months, 250 adults will receive either the drug or a placebo to see if it improves their exerc…
Matched conditions: HEART FAILURE
Phase: PHASE3 • Sponsor: National Institute of Cardiology, Warsaw, Poland • Aim: Disease control
Last updated May 17, 2026 00:47 UTC
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New machine could save more hearts for transplant
Disease control OngoingThis study tests a method to preserve hearts from donors after circulatory death using a machine that keeps them cool and oxygenated. The goal is to increase the number of hearts available for transplant. About 20 adults with heart failure who are already on the transplant list w…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: XVIVO Perfusion • Aim: Disease control
Last updated May 17, 2026 00:46 UTC
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New study tests if opening blocked heart arteries improves survival
Disease control OngoingThis study looks at whether opening a completely blocked heart artery with a procedure called PCI, in addition to taking standard heart medications, helps people live longer or feel better. About 2000 adults with stable heart disease and symptoms like chest pain or shortness of b…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Leif Thuesen • Aim: Disease control
Last updated May 17, 2026 00:46 UTC
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Can the DASH diet help heart failure patients? new study investigates
Disease control OngoingThis pilot study looks at whether the DASH diet (a heart-healthy eating plan) can help people with heart failure better manage their condition. Researchers will track 26 adults' food intake, blood pressure, and heart-related lab results over time. The goal is to see if adding nut…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: University of California, Davis • Aim: Disease control
Last updated May 17, 2026 00:45 UTC
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Lab-Grown heart cells injected into failing hearts: a new hope?
Disease control OngoingThis early-stage trial tests a new treatment for people with severe heart failure caused by blocked arteries. Doctors inject lab-grown heart muscle cells (made from stem cells) directly into the heart to see if they can safely improve pumping strength. Ten participants will be fo…
Matched conditions: HEART FAILURE
Phase: PHASE1, PHASE2 • Sponsor: Heartseed Inc. • Aim: Disease control
Last updated May 17, 2026 00:45 UTC
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New heart Drug's secret powers revealed in small trial
Disease control OngoingThis study looks at how vericiguat, a new heart failure drug, improves heart function during rest and exercise. Thirty adults with heart failure will take either vericiguat or a placebo for about three months. Researchers will measure blood flow, blood pressure, and quality of li…
Matched conditions: HEART FAILURE
Phase: PHASE4 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated May 17, 2026 00:44 UTC
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Smartphone app aims to improve heart failure care
Disease control OngoingThis study tests a mobile app that helps heart failure patients track their symptoms, vital signs, and weight. The app shares this information with doctors to improve medication use and quality of life. About 130 adults with heart failure and reduced pumping function will partici…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated May 17, 2026 00:44 UTC
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New pacemaker system aims to improve heart pacing precision
Disease control OngoingThis study tests the safety and performance of a new pacemaker (Amvia) and a special lead (Solia CSP S) designed to pace the heart's natural electrical system more precisely. It involves 152 people who need a pacemaker or heart resynchronization therapy. Participants are followed…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Biotronik SE & Co. KG • Aim: Disease control
Last updated May 17, 2026 00:44 UTC
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Tiny implant beams heart data from inside the body
Disease control OngoingThis early study tests a new device called the NORM™ system in 25 adults with heart failure. The device is placed in a vein to monitor the heart and send data to a secure database. The goal is to see if the implant is safe and works properly, not to cure heart failure but to help…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Foundry Innovation & Research 1, Limited (FIRE1) • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Heart failure device study aims to boost response rates
Disease control OngoingThis study tests whether placing the left ventricle lead of a heart device at the area with the latest electrical activation improves outcomes for people with heart failure and a wide QRS. About 1000 participants will be randomly assigned to either targeted or standard lead place…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Aarhus University Hospital • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Ancient herb meets modern heart care: can goreisan beat fluid buildup?
Disease control OngoingThis study tests whether adding a traditional Japanese herbal medicine called Goreisan to standard heart failure treatment helps reduce swelling (edema) and improve outcomes. About 1,179 adults with worsening heart failure and fluid overload are participating. The main goal is to…
Matched conditions: HEART FAILURE
Phase: PHASE4 • Sponsor: Takeshi Morimoto • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Could zapping a nerve help failing hearts?
Disease control OngoingThis study tested whether stimulating the vagus nerve in the neck could improve heart function in 118 people with advanced heart failure. Participants had a device implanted to deliver mild electrical pulses to the nerve. The goal was to see if this therapy could reduce heart siz…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Boston Scientific Corporation • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Gum treatment may ease heart failure burden
Disease control OngoingThis study looks at whether treating gum disease (periodontitis) can improve heart failure in adults. About 80 people will get dental cleaning and have their blood and saliva tested for heart failure markers over 6 months. The goal is to see if better gum health can lower a key h…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: University of Taubate • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Could a diabetes drug also mend broken hearts? new study aims to find out
Disease control OngoingThis study is testing whether a newer type of diabetes drug (a GIP/GLP-1 receptor agonist) can improve heart function and blood sugar control in adults who have both chronic heart failure and type 2 diabetes. About 120 participants in Kazakhstan will receive the drug and be monit…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Nazarbayev University • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New heart lead aims to improve pacing for 414 patients in global trial
Disease control OngoingThis study tests a new type of wire (lead) for implantable heart devices like ICDs and CRT-Ds. The lead is designed to pace a specific part of the heart's natural electrical system, which may improve heart function. About 414 adults who already need an ICD or CRT-D will get this …
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Can Spot-Jogging at home help heart failure patients as much as clinic rehab?
Disease control OngoingThis study looks at whether heart failure patients can get the same benefits from doing spot-jogging at home as they would from going to a clinic for rehab. About 40 adults with heart failure will be assigned to either a home program with adjustable jogging intensity or a standar…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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Heart clot showdown: newer blood thinner may beat old standard
Disease control OngoingThis study tests whether a newer type of blood thinner (direct oral anticoagulant, or DOA) works better than the standard older drug (vitamin K antagonist, or VKA) to dissolve blood clots inside the heart. About 340 adults with such clots will be randomly assigned to one of the t…
Matched conditions: HEART FAILURE
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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Could a neck implant cut heart failure deaths? new trial aims to find out
Disease control ENROLLING_BY_INVITATIONThis study tests a device called Barostim that stimulates nerves in the neck to help the body better control heart failure. It involves 2,500 adults with moderate heart failure who still have symptoms despite standard medications. The goal is to see if the device reduces deaths a…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: CVRx, Inc. • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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New heart pump could buy time for failing hearts
Disease control OngoingThis study tests a temporary heart pump called Impella BTR in 10 adults with severe heart failure. The pump is placed inside the body to help the heart pump blood for up to 28 days. The goal is to see if it is safe and can support patients until their heart recovers or they recei…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Abiomed Inc. • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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Which diabetes drug wins for heart failure? 26,000-Patient study aims to find out
Disease control OngoingThis study compares two popular diabetes medications, tirzepatide and semaglutide, in 26,000 adults with type 2 diabetes and a specific type of heart failure (preserved ejection fraction). The goal is to see which drug better reduces the risk of hospitalization for heart failure …
Matched conditions: HEART FAILURE
Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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Teamwork program for heart failure patients shows promise in reducing hospital stays
Disease control OngoingThis study tests a program called De-HF that helps heart failure patients and their family caregivers work as a team to manage the condition at home. The program includes face-to-face and online support to improve quality of life and reduce hospital readmissions. About 232 patien…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: The University of Hong Kong • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New Valve-in-Valve procedure offers hope for failing heart valves
Disease control OngoingThis study tests a less invasive way to replace a failing mitral heart valve without open-heart surgery. About 53 people with a previously implanted surgical valve that is now leaking or narrowed will receive a new valve placed inside the old one. The goal is to see if this proce…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Heart shunt device put to the test in 750-Patient trial
Disease control OngoingThis study tests a small device placed in the heart to help people with a certain type of heart failure (preserved ejection fraction). About 750 participants will either get the device or a sham procedure. The goal is to see if the device reduces heart failure events and improves…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Corvia Medical • Aim: Disease control
Last updated May 14, 2026 12:01 UTC
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No-Implant heart shunt could ease burden of chronic heart failure
Disease control ENROLLING_BY_INVITATIONThis study tests a new device that creates a small passage between the upper chambers of the heart to help relieve pressure in people with chronic heart failure. The device is inserted through a blood vessel and does not leave a permanent implant. About 700 participants with hear…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Alleviant Medical, Inc. • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New heart pacing method tested for better outcomes after valve replacement
Disease control TerminatedThis study compares a newer, more natural heart pacing method (left bundle branch area pacing) to the standard method (right ventricular pacing) in patients who develop heart block after a TAVR procedure. The goal is to see if the newer method improves heart function and reduces …
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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Pacemaker therapy may outperform drugs in mild heart failure, study suggests
Disease control OngoingThis study tests whether early use of a special pacemaker (left bundle branch pacing) can improve heart function better than standard medications in people with heart failure whose heart pumps slightly less than normal. The trial involves 36 adults with symptoms despite medicatio…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Fu Wai Hospital, Beijing, China • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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Heart repair drug shows promise for diabetic kidney patients
Disease control ENROLLING_BY_INVITATIONThis study tests whether the drug finerenone can reduce scarring and fat buildup in the heart muscle of people with diabetic kidney disease and heart failure. Forty participants will take finerenone daily for six months and undergo heart scans before and after treatment. The goal…
Matched conditions: HEART FAILURE
Phase: PHASE4 • Sponsor: Cathay General Hospital • Aim: Disease control
Last updated May 12, 2026 13:42 UTC
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New pacing method may improve heart function after ablation
Disease control OngoingThis study looks at 82 heart failure patients with atrial fibrillation who need a heart ablation and a pacemaker. It compares a newer pacing method (conduction system pacing) to the standard method (biventricular pacing) to see if the newer one works just as well or better at imp…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: University Medical Centre Ljubljana • Aim: Disease control
Last updated May 11, 2026 20:54 UTC
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Foot scanner could keep heart failure patients out of hospital
Disease control OngoingThis study tests a device that scans your feet and lower legs to spot early fluid buildup, a key sign of worsening heart failure. The goal is to catch problems early so doctors can adjust treatment and avoid hospital stays. About 186 adults with heart failure who already take wat…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Heartfelt Technologies • Aim: Disease control
Last updated May 11, 2026 20:53 UTC
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Could a diabetes drug ease heart strain in fontan patients?
Disease control ENROLLING_BY_INVITATIONThis study tests whether a daily pill called dapagliflozin can help adults with Fontan circulation, a heart condition from birth. Researchers want to see if it lowers pressure in the veins and improves exercise ability. About 29 adults will take the drug for 4 weeks and have chec…
Matched conditions: HEART FAILURE
Phase: PHASE4 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated May 11, 2026 20:51 UTC
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New heart device tested in first human study
Disease control OngoingThis study tests a new implantable defibrillator (ICD) called CorSky in 52 people with fast heartbeats or heart failure. The device delivers shocks to restore normal heart rhythm. Researchers will check if it works safely and performs well over 12 months. Participants attend foll…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Biotronik Australia Pty Ltd. • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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New heart device aims to ease breathing and fatigue in heart failure
Disease control OngoingThis study tests a small device called the APTURE shunt, placed in the heart to help reduce pressure and improve symptoms in people with heart failure. About 100 participants will receive either the shunt or a sham procedure to see if it safely improves exercise ability and quali…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated May 11, 2026 20:41 UTC
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New heart preservation method could save more lives in transplants
Disease control OngoingThis study tests a new device that keeps donated hearts healthy without stopping blood flow during transport. It involves 141 adults getting a heart transplant from extended-criteria donors. The goal is to see if this method helps more patients survive one year after transplant.
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: XVIVO Perfusion • Aim: Disease control
Last updated May 11, 2026 20:40 UTC
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New heart shunt aims to ease burden of heart failure
Disease control OngoingThis early study tests a device that creates a small passage in the heart to help relieve pressure in people with symptomatic heart failure. About 71 participants will receive the implant and be monitored for safety and how well the device works. The goal is to see if the shunt c…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated May 11, 2026 20:39 UTC
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New heart shunt device shows promise for heart failure patients
Disease control OngoingThis study tests a small device called the APTURE shunt, which is placed in the heart to help reduce fluid buildup and ease symptoms of heart failure. About 45 people with moderate to severe heart failure and reduced pumping function will take part. The main goal is to see if the…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Can a simple Anti-Inflammatory shot stop heart failure after a heart attack?
Disease control OngoingThis study tests whether a drug called anakinra, which reduces inflammation, can help prevent heart failure in people who have had a heart attack. About 84 adults who recently had a severe heart attack will receive the drug. The goal is to see if blocking the body's inflammatory …
Matched conditions: HEART FAILURE
Phase: PHASE2 • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated May 07, 2026 18:42 UTC
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New heart implant aims to help failing hearts pump better
Disease control OngoingThis study is testing a device called the OPTIMIZER Smart, which is implanted in the chest to send mild electrical signals to the heart. The goal is to see if it safely improves heart function and reduces hospital visits in 620 adults with moderate-to-severe heart failure. Partic…
Matched conditions: HEART FAILURE
Sponsor: Impulse Dynamics • Aim: Disease control
Last updated May 07, 2026 18:41 UTC
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New No-Implant shunt could ease heart failure burden
Disease control ENROLLING_BY_INVITATIONThis study tests a new device that creates a small passage in the heart to relieve pressure, without leaving a permanent implant. It is for people with heart failure and reduced pumping ability. The trial is double-blind and compares the procedure to a sham (fake) procedure to se…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Alleviant Medical, Inc. • Aim: Disease control
Last updated May 05, 2026 11:56 UTC
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New heart pump driver aims to keep kids alive until transplant
Disease control ENROLLING_BY_INVITATIONThis study is testing a new driving system for the Berlin Heart EXCOR, a heart pump used in children with severe heart failure who are waiting for a heart transplant. The goal is to see if the new system works safely and effectively. About 40 children will take part, and the stud…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Berlin Heart, Inc • Aim: Disease control
Last updated May 04, 2026 16:31 UTC
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Heart failure device registry aims to prove Real-World benefits
Disease control OngoingThis study is a registry that follows 5,000 heart failure patients who have already received a Barostim implant. The device is designed to improve symptoms like shortness of breath and fatigue. Researchers will track how well the therapy works and if it is safe over time in every…
Matched conditions: HEART FAILURE
Sponsor: CVRx, Inc. • Aim: Disease control
Last updated May 04, 2026 16:24 UTC
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Heart pump patients get team care boost in new study
Disease control ENROLLING_BY_INVITATIONThis study looks at whether a special clinic with a team of experts can improve quality of life and reduce hospital visits for people with a mechanical heart pump (VAD). About 110 patients and their caregivers will take part. The goal is to see if this team approach helps patient…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 04, 2026 16:21 UTC
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New ER strategy for heart failure: urine test guides water pill dosing
Disease control OngoingThis study compares a new method of giving diuretics (water pills) guided by urine sodium levels to standard care for adults with acute heart failure in the emergency department. About 474 participants will be randomly assigned to either the urine-guided approach or usual care. T…
Matched conditions: HEART FAILURE
Phase: PHASE2 • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated May 01, 2026 15:56 UTC
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New study aims to find the best ablation technique for heart failure patients with stubborn irregular heartbeat
Disease control OngoingThis study looks at 300 adults with both persistent atrial fibrillation (a long-lasting irregular heartbeat) and heart failure. Researchers are testing different catheter ablation strategies to see which one works best to prevent heart-related death, hospital stays, or urgent vis…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Xu Liu • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
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Could a diabetes pill save lives in severe kidney disease? major trial underway.
Disease control ENROLLING_BY_INVITATIONThis study tests whether dapagliflozin, a drug originally for diabetes, can reduce the risk of death, kidney failure, and heart failure hospitalizations in 1,750 people with severe chronic kidney disease, including those on dialysis or with a kidney transplant. Participants will …
Matched conditions: HEART FAILURE
Phase: PHASE3 • Sponsor: University Medical Center Groningen • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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Simple Finger-Prick test could uncover hidden heart failure
Diagnosis ENROLLING_BY_INVITATIONThis study looks at whether a quick blood test (NT-proBNP) can help doctors find heart failure earlier in adults who take water pills (loop diuretics) but don't yet have a heart failure diagnosis. About 400 people from GP practices in Jersey will take part. Some GP practices will…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Government of Jersey • Aim: Diagnosis
Last updated May 17, 2026 00:53 UTC
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A simple wrist sensor could spot heart failure before It's too late
Diagnosis OngoingThis study tests a small, wearable sensor that reads pulse patterns to help detect heart failure. Heart failure is often missed in early stages because its symptoms are similar to other conditions. The sensor uses principles from Traditional Chinese Medicine and artificial intell…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: National Heart Centre Singapore • Aim: Diagnosis
Last updated May 17, 2026 00:53 UTC
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Hidden heart failure: new screening could save lives in diabetes patients
Diagnosis OngoingThis study tests a targeted screening approach to detect undiagnosed heart failure in 706 adults aged 40+ with type 1 or type 2 diabetes who also have additional heart risk factors. Participants are randomly assigned to receive the screening or usual care, and researchers track h…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: NHS Greater Glasgow and Clyde • Aim: Diagnosis
Last updated May 17, 2026 00:46 UTC
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AI and Finger-Prick test could spot hidden heart failure in pacemaker patients
Diagnosis ENROLLING_BY_INVITATIONThis study aims to find a faster, cheaper way to screen for heart failure in people with pacemakers. About 1 in 3 pacemaker patients may have undiagnosed heart failure, but current detection requires a lengthy, expensive ultrasound. Researchers will test if an AI-powered handheld…
Matched conditions: HEART FAILURE
Sponsor: University of Leeds • Aim: Diagnosis
Last updated May 13, 2026 16:03 UTC
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Heart patients get Chef-Made meals to boost recovery
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether providing medically tailored meals to heart failure patients after they leave the hospital helps them recover better. Researchers will enroll 85 adults on Medicaid or Medicare and track how many meals are successfully delivered and how patients rate the s…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated May 17, 2026 00:47 UTC
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Heart failure study questions whether common heart meds are needed for some seniors
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether older adults (age 60+) with a type of heart failure called HFpEF can safely stop taking beta-blockers and feel better. Participants are randomly assigned to either gradually reduce their beta-blocker dose or continue taking it for about 4 months. The g…
Matched conditions: HEART FAILURE
Phase: PHASE4 • Sponsor: Weill Medical College of Cornell University • Aim: Symptom relief
Last updated May 17, 2026 00:45 UTC
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Heart failure drug showdown: which pill flushes salt better?
Symptom relief TerminatedThis study aimed to see if an extended-release version of the water pill torsemide helps heart failure patients get rid of salt better than the standard version, especially after a salty lunch. Participants would have taken each pill for a week and collected urine samples. Howeve…
Matched conditions: HEART FAILURE
Phase: PHASE2 • Sponsor: Sarfez Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated May 17, 2026 00:44 UTC
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Step by step: new study tests walking therapy for heart failure patients
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether a 9-month walking program can help people with heart failure walk farther and feel better in daily life. About 200 adults with stable heart failure will either join the walking program or continue with standard care. The goal is to see if increasing da…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Universidad de Granada • Aim: Symptom relief
Last updated May 17, 2026 00:44 UTC
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Heart failure patients test ketone drink for better pumping
Symptom relief OngoingThis study looks at whether a dietary supplement called ketone ester can improve heart function in people with heart failure. About 50 participants will receive either the supplement or a placebo for 12 weeks. Heart function is measured with MRI scans before and after the treatme…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Same-Day pacemaker implant: a game changer for heart failure?
Symptom relief OngoingThis study looks at whether people with heart failure can safely receive a special pacemaker (CRT-P) and go home the same day, instead of staying overnight in the hospital. Researchers are tracking serious side effects for six months after the procedure. The goal is to see if a o…
Matched conditions: HEART FAILURE
Sponsor: Biotronik SE & Co. KG • Aim: Symptom relief
Last updated May 15, 2026 11:52 UTC
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Exercise may boost heart health in lung hypertension patients
Symptom relief TerminatedThis study looks at whether a supervised exercise program can improve heart function and quality of life for people with heart failure and pulmonary hypertension (high blood pressure in the lungs). Researchers will measure oxygen use during exercise and blood pressure in the lung…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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Can VR sharpen your memory? new study targets heart failure patients
Symptom relief OngoingThis study tests whether a combination of virtual reality exercises and computer-based brain training can improve memory and thinking skills in older adults with heart failure who have mild cognitive impairment. Researchers will enroll 172 participants aged 55 and older. The goal…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated May 14, 2026 12:03 UTC
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Heart help for cancer survivors: exercise and diet study shows promise
Symptom relief OngoingThis study looks at whether teaching cancer survivors with mild to moderate heart failure about exercise and diet can help them change their lifestyle. About 85 people will take part. The goal is to see if this approach can ease symptoms and improve daily life.
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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Video chat boosts heart failure Self-Care in new trial
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether adding a video call education session helps heart failure patients improve their self-care skills, like monitoring weight and symptoms. About 100 adults with heart failure will take part. All receive standard teaching; half also get a video call three mon…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Maria Jose Santi Cano • Aim: Symptom relief
Last updated May 12, 2026 13:43 UTC
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Gamification gets seniors walking after hospital discharge
Symptom relief OngoingThis study tests whether fun challenges (gamification) and personal coaching can help older adults become more active after leaving the hospital. About 350 people aged 50+ with conditions like high blood pressure or heart failure will wear a Fitbit to track steps. The goal is to …
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated May 11, 2026 20:46 UTC
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Yoga may boost brain health in heart failure patients
Symptom relief ENROLLING_BY_INVITATIONThis study explores whether a 12-week yoga program can improve brain function and thinking skills in people aged 55+ who have both heart failure and mild cognitive impairment. Researchers will use brain scans, memory tests, and blood samples to measure changes. The goal is to see…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Auburn University • Aim: Symptom relief
Last updated May 11, 2026 20:37 UTC
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Haiti heart watch: 3,000 adults to reveal hidden cardiovascular risks
Knowledge-focused OngoingThis study follows about 3,000 adults in Port-au-Prince, Haiti, for up to 7 years to track heart disease risks like high blood pressure, diabetes, and smoking. Researchers will measure how common these risks are and how they lead to heart attacks, strokes, or heart failure. The g…
Matched conditions: HEART FAILURE
Sponsor: Weill Medical College of Cornell University • Aim: Knowledge-focused
Last updated May 17, 2026 00:53 UTC
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Heart failure Patients' balance and brain function under the microscope
Knowledge-focused OngoingThis study looks at balance and thinking skills in middle-aged and older adults with heart failure who are in a post-acute care program. Researchers will compare them to healthy people of the same age and track changes one and three months after leaving the hospital. The goal is …
Matched conditions: HEART FAILURE
Sponsor: Chang Chia-Jung • Aim: Knowledge-focused
Last updated May 17, 2026 00:52 UTC
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Smart patch could replace needle for heart check
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests if a wearable sensor can accurately estimate the heart's pumping ability (LVEF) in 50 adults who are already scheduled for an echocardiogram. The goal is to see if the sensor matches the standard ultrasound test. If successful, this could lead to easier, more fre…
Matched conditions: HEART FAILURE
Sponsor: Skribe Medical • Aim: Knowledge-focused
Last updated May 17, 2026 00:50 UTC
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Hospital mobility game study pulled before it began
Knowledge-focused TerminatedThis study aimed to see if using wearable step counters and smartphone games could encourage hospital patients with heart conditions to walk more. It planned to enroll adults aged 50 and older admitted to medicine or cardiology floors. However, the study was withdrawn before any …
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 17, 2026 00:49 UTC
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Heart failure drug study pulled before starting
Knowledge-focused TerminatedThis study aimed to compare an extended-release version of the water pill torsemide to the standard immediate-release version in people with stable heart failure. Researchers planned to measure how much salt the body gets rid of after taking each type. However, the study was with…
Matched conditions: HEART FAILURE
Phase: PHASE4 • Sponsor: Sarfez Pharmaceuticals, Inc. • Aim: Knowledge-focused
Last updated May 17, 2026 00:49 UTC
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Stiff arteries after heart attack? study aims to predict who will develop heart failure
Knowledge-focused OngoingThis study looks at 2000 people who had a heart attack to see if measuring the stiffness of their blood vessels one month later can help predict future problems like heart failure, another heart attack, or stroke. Participants are enrolled within 48 hours of their heart attack an…
Matched conditions: HEART FAILURE
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 17, 2026 00:49 UTC
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German heart failure patients monitored on new drug dapagliflozin
Knowledge-focused OngoingThis study tracks over 800 heart failure patients in Germany who are starting dapagliflozin, a recently approved drug. Researchers will observe how long patients stay on the medication, any side effects, and changes in symptoms and quality of life. The goal is to understand how t…
Matched conditions: HEART FAILURE
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated May 17, 2026 00:49 UTC
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Scientists collect heart tissue to unlock secrets of heart failure
Knowledge-focused ENROLLING_BY_INVITATIONThis study collects tissue and blood samples from 200 people with advanced heart failure who are getting a heart pump or a heart transplant. Researchers will use these samples to learn more about heart failure. No new treatments or drugs are being tested, and the samples do not c…
Matched conditions: HEART FAILURE
Sponsor: Intermountain Health Care, Inc. • Aim: Knowledge-focused
Last updated May 17, 2026 00:46 UTC
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Eye scans may reveal hidden clues about heart failure
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests whether a simple, non-invasive eye scan can help doctors assess heart failure severity. Researchers will look at blood vessels in the retina and compare them to standard heart failure tests. The goal is to see if retinal imaging can provide useful information abo…
Matched conditions: HEART FAILURE
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated May 17, 2026 00:45 UTC
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New web tool aims to give heart failure patients a voice in End-of-Life decisions
Knowledge-focused OngoingThis study tests a web-based platform called 'My Voice' that helps heart failure patients and their caregivers learn about the disease, clarify their goals for end-of-life care, and share those wishes with doctors and family. About 244 patients in Singapore are taking part. The g…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Duke-NUS Graduate Medical School • Aim: Knowledge-focused
Last updated May 17, 2026 00:45 UTC
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New study tracks heart recovery after tricuspid valve replacement
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at heart failure patients with a severe leaky tricuspid valve who received a new valve through a tube in a blood vessel (transcatheter replacement). It focuses on those who had unstable blood pressure right after the procedure. Researchers want to understand how …
Matched conditions: HEART FAILURE
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated May 17, 2026 00:45 UTC
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Can a sleep machine boost heart efficiency? new study investigates
Knowledge-focused OngoingThis study looks at how a breathing device called adaptive servo-ventilation (ASV) affects heart energy use and nerve function in people with heart failure and sleep apnea. Researchers will measure heart metabolism and efficiency using PET scans and heart rate monitoring. The goa…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Knowledge-focused
Last updated May 17, 2026 00:44 UTC
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2000 heart failure patients join study to unlock disease secrets
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to collect blood, urine, and stool samples from 2000 adults with heart failure to better understand how the disease progresses. Researchers will analyze these samples to find proteins and other factors linked to worsening heart function. Participants have one visi…
Matched conditions: HEART FAILURE
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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AI and heart data aim to predict potassium levels, but study never started
Knowledge-focused TerminatedThis study planned to use a computer program (machine learning) and a simple heart test (single-lead ECG) to predict potassium levels in the blood of hospitalized patients. Researchers would have analyzed data from a previous study at Brigham and Women's Hospital. However, the st…
Matched conditions: HEART FAILURE
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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AI predicts hospital stays, but study never started
Knowledge-focused TerminatedThis study aimed to see if a computer program could predict how long patients would stay in a home hospital. Researchers planned to use information from past patients to train the computer model. However, the study was withdrawn before any participants were enrolled.
Matched conditions: HEART FAILURE
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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5,000 patients help doctors learn better ways to talk about end-of-life care
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to find better ways for doctors and patients to talk about what matters most when facing a serious illness like cancer, heart failure, COPD, or dementia. Researchers will track how often and how early these conversations happen in the last six months of life. The …
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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New MRI study aims to spot heart failure before it starts
Knowledge-focused ENROLLING_BY_INVITATIONThis study uses advanced heart MRI scans to better understand early-stage heart failure in people with risk factors like diabetes, high blood pressure, or obesity. Researchers will follow 3000 participants over time to see how these scans can help predict who might develop worsen…
Matched conditions: HEART FAILURE
Sponsor: Chinese Academy of Medical Sciences, Fuwai Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Heart test race gap under investigation
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether standard blood tests for heart failure show different results in African American patients compared to Caucasian patients. Researchers will review medical records of 400 adults newly diagnosed with heart failure to see if race affects biomarker levels …
Matched conditions: HEART FAILURE
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Gene test: does sitagliptin work better for some?
Knowledge-focused OngoingThis study looks at how the diabetes drug sitagliptin affects people who have a natural genetic change that lowers their DPP4 levels. Researchers will compare 20 adults with and without this gene change to see if the drug lowers blood sugar more effectively. The goal is to unders…
Matched conditions: HEART FAILURE
Phase: PHASE4 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Your own personal drug trial: a new way to tweak heart meds
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests a personalized approach called N-of-1 trials to help older adults with a type of heart failure (HFpEF) decide whether to continue or stop taking beta-blockers. About 20 participants will try different medication schedules and report their confidence and preferenc…
Matched conditions: HEART FAILURE
Phase: PHASE4 • Sponsor: Weill Medical College of Cornell University • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Can a smartphone app help heart patients take the right dose?
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests whether a phone app called StudyU can help people with heart failure reach the recommended dose of their beta blocker medicine. Five adults aged 65 and older with heart failure will use the app. The goal is to see if the app is practical and acceptable for patien…
Matched conditions: HEART FAILURE
Phase: PHASE4 • Sponsor: Weill Medical College of Cornell University • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Hospital at home: a new way to treat illness without leaving your living room
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether treating patients at home, instead of in a hospital, can lead to better health outcomes and happier patients. About 9,654 adults with conditions like heart failure, infections, or diabetes will receive hospital-level care in their own homes. Researcher…
Matched conditions: HEART FAILURE
Sponsor: OSF Healthcare System • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Can cash and coaching get heart patients to rehab?
Knowledge-focused OngoingThis study looks at new ways to help heart patients attend cardiac rehab, a program that only 30% of eligible people currently use. Researchers will test if offering $50, case management, text messages, and coaching helps more patients go. They will also compare four different wa…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Baystate Medical Center • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Family doctors train to spot heart problems with ultrasound
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether family doctors can be trained to perform focused heart ultrasounds (FoCUS) accurately. About 500 patients with suspected heart issues will have both a doctor-performed ultrasound and a standard cardiologist exam. The goal is to see how well the doctors…
Matched conditions: HEART FAILURE
Sponsor: Societat Catalana de Medicina Familiar i Comunitària, Assoc. (CAMFiC) • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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Blood test during heart procedure may predict pacemaker success
Knowledge-focused OngoingThis study looks at 65 adults with heart failure who are getting a special pacemaker called a CRT device. During the procedure, doctors will take a small blood sample from a vein near the heart to measure oxygen and other gas levels. The goal is to see if these blood gas levels c…
Matched conditions: HEART FAILURE
Sponsor: Trakya University • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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New study aims to boost heart failure care for veterans
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at ways to help pharmacists manage heart failure medications more often for veterans. About 400 pharmacists from 22 VA sites will take part. Some will get extra education and feedback, while others will get education alone. The goal is to see which method leads t…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated May 13, 2026 16:01 UTC
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Heart study aims to cut unnecessary pacemaker implants by half
Knowledge-focused OngoingThis study looks at 500 people with heart failure to see if using an ultrasound test (echocardiography) to measure how well the heart's chambers work together can better decide who needs a cardiac resynchronization therapy (CRT) device. Currently, 30-40% of patients don't improve…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated May 13, 2026 16:01 UTC
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Heart monitor could uncover hidden stroke risk in heart failure patients
Knowledge-focused OngoingThis study looks at whether a small device placed under the skin (an implantable cardiac monitor) can find hidden atrial fibrillation in people with heart failure who are at high risk for stroke. About 477 participants will either get the monitor or standard care. The goal is to …
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated May 13, 2026 16:01 UTC
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Massive study tracks 10,000 sleep apnea patients to uncover heart attack and death links
Knowledge-focused OngoingThis study looks at 10,000 people who have both sleep apnea and high blood pressure. Researchers will track them over many years to see how well they use their sleep apnea machine (PAP) and blood pressure medicines, and whether that affects their risk of heart attacks, strokes, h…
Matched conditions: HEART FAILURE
Sponsor: Vastra Gotaland Region • Aim: Knowledge-focused
Last updated May 12, 2026 13:43 UTC
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Heart pacing showdown: which method wins for heart failure?
Knowledge-focused OngoingThis study looks at real-world data from 6,000 people with heart failure to compare two types of heart pacing: conduction system pacing (CSP) and biventricular pacing (BVP). The goal is to see if CSP is as safe and effective as BVP in reducing complications and hospital stays. Re…
Matched conditions: HEART FAILURE
Sponsor: Medtronic Cardiac Rhythm and Heart Failure • Aim: Knowledge-focused
Last updated May 12, 2026 13:41 UTC
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New study aims to catch hidden muscle loss in heart patients
Knowledge-focused OngoingThis study looks for better ways to detect muscle loss (sarcopenia) in people with heart failure. Many heart failure patients also have muscle loss, which makes their condition worse. Researchers will measure muscle mass, strength, and walking speed in 80 adults aged 50 and older…
Matched conditions: HEART FAILURE
Sponsor: University of Liverpool • Aim: Knowledge-focused
Last updated May 11, 2026 20:52 UTC
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Heart device study seeks to unlock secrets of arm strength and survival
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how well people with heart failure and implanted heart devices (like defibrillators or pacemakers) can use their arms and hands. Researchers will test arm strength, endurance, and daily function in 72 adults. The goal is to find links between arm function and …
Matched conditions: HEART FAILURE
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated May 11, 2026 20:52 UTC
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Your voice could warn of heart failure days before symptoms start
Knowledge-focused OngoingThis study tests whether a smartphone app can catch early signs of heart failure getting worse by analyzing daily voice recordings. 123 adults who were recently hospitalized for heart failure will record their voice and answer symptom questions for 6 months. The app's predictions…
Matched conditions: HEART FAILURE
Sponsor: Noah Labs • Aim: Knowledge-focused
Last updated May 11, 2026 20:49 UTC
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Heart imaging study aims to predict who gets better
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at 180 adults newly diagnosed with heart failure and reduced pumping ability. Researchers use multiple heart scans (MRI, CT, PET, ultrasound) to see if they can predict how well the heart will recover over 3-12 months. A smaller part of the study tests a higher d…
Matched conditions: HEART FAILURE
Phase: PHASE4 • Sponsor: Gødstrup Hospital • Aim: Knowledge-focused
Last updated May 11, 2026 20:48 UTC
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New tech aims to cut errors when patients are moved between hospitals
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests a new digital tool that helps hospitals share patient information more reliably when a person is transferred from one hospital to another. The goal is to reduce medical mistakes and improve safety. About 1,000 adults being transferred to a major hospital will tak…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 11, 2026 20:47 UTC
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New digital tool aims to improve heart failure care in virtual doctor visits
Knowledge-focused OngoingThis study tests a new computer tool that helps doctors prescribe the right heart failure medications during phone or video visits. Researchers will compare the new tool to an existing one in 20 cardiology clinics. The goal is to see if the tool works well and is easy to use in v…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated May 11, 2026 20:46 UTC
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New heart drug SHR-6934 takes first step in human safety trial
Knowledge-focused OngoingThis early-stage study tests whether a new drug called SHR-6934 is safe in healthy people. About 72 volunteers receive either the drug or a placebo injection. The goal is to check for side effects and how the drug moves through the body, not to treat any disease.
Matched conditions: HEART FAILURE
Phase: PHASE1 • Sponsor: Beijing Suncadia Pharmaceuticals Co., Ltd • Aim: Knowledge-focused
Last updated May 11, 2026 20:41 UTC
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Can a simple risk score stop pacemakers from weakening the heart?
Knowledge-focused OngoingThis study looks at 4,500 people with pacemakers or similar heart devices to find out who is most likely to develop a condition where the heart weakens over time. Researchers will use routine medical and device data to create a risk score that helps doctors choose the best pacing…
Matched conditions: HEART FAILURE
Sponsor: Insel Gruppe AG, University Hospital Bern • Aim: Knowledge-focused
Last updated May 11, 2026 20:40 UTC
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Smart nudge: personalized alerts aim to boost heart failure prescriptions
Knowledge-focused OngoingThis study tests a new computer tool that gives doctors personalized reminders when prescribing heart failure medications. The goal is to see if tailoring alerts to each doctor's past prescribing habits leads to more patients getting the right drugs. About 764 doctors from cardio…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated May 11, 2026 20:39 UTC
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Can a heart device alert predict trouble? new study investigates
Knowledge-focused OngoingThis study looks at how well a feature called TriageHF, built into Medtronic heart devices, can warn doctors when a patient's heart failure is getting worse. About 2200 people with these devices are being followed to see if high-risk alerts correctly predict hospital stays or dea…
Matched conditions: HEART FAILURE
Sponsor: Medtronic • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC
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New registry tracks heart failure patients with unexpectedly good heart function
Knowledge-focused OngoingThis study is a registry that collects health information from 700 adults with heart failure whose heart pumping ability has either improved or is naturally high. Researchers will track their health over time to understand how these patients do. No new treatments or procedures ar…
Matched conditions: HEART FAILURE
Sponsor: Jagiellonian University • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC
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8,000-Patient MRI study aims to unlock secrets of heart disease
Knowledge-focused OngoingThis study uses a special MRI technique called T1 mapping to measure changes in heart muscle tissue. Researchers will follow 8,000 adults who are already having a heart MRI to see if these measurements can help predict future health problems like heart failure or death. The goal …
Matched conditions: HEART FAILURE
Sponsor: Johann Wolfgang Goethe University Hospital • Aim: Knowledge-focused
Last updated May 08, 2026 12:03 UTC
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Mayo clinic tracks 1,600 heart attack survivors to predict heart failure
Knowledge-focused OngoingThis study follows 1,599 people who had their first heart attack to see how the heart's shape and function change over time. Researchers want to understand which patterns of remodeling lead to heart failure. Participants are from several Minnesota counties and are not receiving a…
Matched conditions: HEART FAILURE
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 08, 2026 12:02 UTC
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Heart device study aims to improve care for thousands
Knowledge-focused OngoingThis study follows over 3,000 heart failure patients who get a special heart device (CRT) to see how they do over time. The goal is to track hospital visits, deaths, and device problems to find better ways to use the device. Participants must be getting the device for the first t…
Matched conditions: HEART FAILURE
Sponsor: Biotronik SE & Co. KG • Aim: Knowledge-focused
Last updated May 07, 2026 18:42 UTC
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Can a simple blood test save lives of fast-breathing patients?
Knowledge-focused OngoingThis study looks at whether doing early blood tests for heart strain and giving doctors a clear alert in the patient's chart can improve outcomes for adults admitted to the hospital with fast breathing (tachypnea). About 574 participants will be randomly assigned to either get th…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: University Hospital, Akershus • Aim: Knowledge-focused
Last updated May 07, 2026 18:38 UTC
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Heart failure drug may boost red blood cells and protect organs
Knowledge-focused OngoingThis study reviews medical records of 85 adults with chronic heart failure to see if SGLT2 inhibitors (a type of diabetes drug) improve red blood cell production and heart/kidney function over 12 months. Researchers compare those who started the drug to a similar group who did no…
Matched conditions: HEART FAILURE
Sponsor: University Medical Centre Ljubljana • Aim: Knowledge-focused
Last updated May 04, 2026 16:30 UTC
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AI voice assistant listens to heart failure patients
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests whether an AI voice assistant can accurately capture health information from heart failure patients. About 100 adults receiving heart care at Stanford will use the tool to report their symptoms and well-being. Researchers will compare the AI's summaries to expert…
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated May 04, 2026 16:20 UTC
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Heart failure study tracks metabolic shifts from common drug
Knowledge-focused ENROLLING_BY_INVITATIONThis study watches 40 adults with heart failure to see how SGLT2 inhibitors affect their body's energy use and blood markers. Participants do a walking test, a leg MRI, and give blood samples before and after starting the drug. The goal is to understand the early metabolic change…
Matched conditions: HEART FAILURE
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC
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Heart monitor study aims to predict heart failure Flare-Ups
Knowledge-focused OngoingThis study is collecting information from small heart monitors placed under the skin of 525 people with heart failure. The goal is to learn how sensor data might relate to heart failure events like hospital visits. Participants have moderate heart failure and are not expected to …
Matched conditions: HEART FAILURE
Phase: NA • Sponsor: Boston Scientific Corporation • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:00 UTC
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Massive 20-Year study maps the hidden path to heart disease
Knowledge-focused OngoingThis long-term study aims to understand how early, hidden signs of heart disease develop and predict future heart attacks, strokes, and heart failure. It follows over 6,400 adults from four different ethnic groups who started the study with no known heart disease. Researchers use…
Matched conditions: HEART FAILURE
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Apr 20, 2026 16:14 UTC