Ancient herb may help heart patients shed excess fluid
NCT ID NCT04691700
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a traditional Japanese herbal medicine called Goreisan to standard heart failure treatment can help reduce fluid buildup (edema) in the body. About 1,179 adults with worsening heart failure and signs of fluid overload are being randomly assigned to receive either Goreisan plus standard care or standard care alone. The main goals are to see if Goreisan helps clear fluid and reduces the risk of death or hospitalization.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Goreisan (TJ-17), a traditional Japanese herbal medicine
What this could lead to
If it works, this could provide a way to reduce or stop diuretic use in heart failure patients while controlling fluid buildup.
What could go wrong
This is a Phase 4 trial, but results are not yet published. The herbal medicine may not improve outcomes or could interact with other drugs.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Kyoto University Graduate School of Medicine
Kyoto, Kyoto, 606-8507, Japan