Ancient herb may help heart patients shed excess fluid

NCT ID NCT04691700

Ongoing Symptom relief Sponsor: Takeshi Morimoto Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a traditional Japanese herbal medicine called Goreisan to standard heart failure treatment can help reduce fluid buildup (edema) in the body. About 1,179 adults with worsening heart failure and signs of fluid overload are being randomly assigned to receive either Goreisan plus standard care or standard care alone. The main goals are to see if Goreisan helps clear fluid and reduces the risk of death or hospitalization.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Goreisan (TJ-17), a traditional Japanese herbal medicine
What this could lead to: If it works, this could provide a way to reduce or stop diuretic use in heart failure patients while controlling fluid buildup.
What could go wrong: This is a Phase 4 trial, but results are not yet published. The herbal medicine may not improve outcomes or could interact with other drugs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CLINICAL TRIAL are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

congestive heart failure Edema heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CLINICAL TRIAL EDEMA HEART FAILURE KAMPO MEDICINE TRADITIONAL JAPANESE MEDICINE

Contacts and locations

Locations

Kyoto University Graduate School of Medicine

Kyoto, Kyoto, 606-8507, Japan

More trials for these conditions

Other studies related to the condition(s) this trial covers.