Could a drink improve heart failure? new study tests ketone esters
NCT ID NCT05924802
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a ketone ester supplement, taken three times a day for 12 weeks, can improve heart function in people with heart failure. Fifty participants will be randomly assigned to receive the supplement or a placebo. Heart function will be measured using cardiac MRI at the start and end of the study.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ketone ester (dietary supplement)
- What this could lead to
- If it works, this could point toward a simple dietary supplement to help manage heart failure.
- What could go wrong
- This is a small, early-stage study (50 people) looking at MRI changes, not hard outcomes like survival. The supplement may show no benefit or cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cardiovascular Innovation Research Center
Cleveland, Ohio, 44195, United States
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