Can a diabetes drug boost heart function in non-diabetic patients?

NCT ID NCT05182658

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether empagliflozin, a drug typically used for diabetes, can help people with hypertrophic cardiomyopathy (a thickened heart muscle) who do not have diabetes. About 250 adults will receive either the drug or a placebo daily for 12 months. The main goals are to see if the drug improves exercise capacity (measured by oxygen use during exercise) and quality of life (via a heart-disease questionnaire).

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medical University of Bialystok

    Bialystok, Poland

  • National Institute of Cardiology

    Warsaw, Poland

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