Can a diabetes drug boost heart function in non-diabetic patients?

NCT ID NCT05182658

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether empagliflozin, a drug typically used for diabetes, can help people with hypertrophic cardiomyopathy (a thickened heart muscle) who do not have diabetes. About 250 adults will receive either the drug or a placebo daily for 12 months. The main goals are to see if the drug improves exercise capacity (measured by oxygen use during exercise) and quality of life (via a heart-disease questionnaire).

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Conditions

The condition(s) this trial relates to.

heart failure hypertrophic cardiomyopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medical University of Bialystok

    Bialystok, Poland

  • National Institute of Cardiology

    Warsaw, Poland