New heart shunt device could ease heart failure symptoms

NCT ID NCT04000607

Ongoing Disease control Sponsor: Edwards Lifesciences Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a device called the APTURE shunt, which is implanted in the heart to create a small passage that may help relieve pressure. It involves 45 people with symptomatic heart failure who are already on standard medications. The goal is to see if the device is safe and can improve symptoms and reduce the need for hospital care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: APTURE transcatheter shunt system (a device implanted in the heart to create a small passage between chambers)
What this could lead to: If it works, this device could offer a new way to relieve pressure in the heart and improve symptoms for people with heart failure, potentially reducing hospital stays.
What could go wrong: This is an early exploratory study with only 45 participants, so results may not apply to everyone. There are risks from the implant procedure, including heart, brain, or kidney complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE

Contacts and locations

Locations

St. Michael's Hospital

Toronto, Ontario, M5B 1W8, Canada
University of Ottawa Heart Institute

Ottawa, Ontario, Canada

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