Edwards Lifesciences

This study aims to determine whether early valve replacement or careful monitoring works better for older adults with moderate aortic valve narrowing. Researchers will compare two approaches: implanting a new heart valve through a minimally invasive procedure versus regular check…

This study is testing a replacement heart valve for adults and children (weighing at least 44 lbs) who were born with heart defects and now have a leaky or narrowed pulmonary valve. Doctors will implant the new valve using a catheter through a blood vessel, avoiding open-heart su…

This study is testing a new device called the SAPIEN M3 System to replace a leaky mitral heart valve without major open-heart surgery. It's for people with severe symptoms from their leaky valve who are not good candidates for standard surgical or other catheter-based treatments.…

This study is collecting real-world safety and performance data on a specific artificial mitral heart valve (MITRIS RESILIA) after it has been approved for use. It will follow 250 Chinese adults who have received this valve to replace their own faulty mitral valve. The main goal …

This study is testing a new device called the PASCAL system, which is designed to repair a leaky tricuspid heart valve without open-heart surgery. It will compare the device plus standard medical care against medical care alone in about 870 patients who have severe symptoms and a…

This study is testing a new, less invasive heart valve called the SAPIEN X4. It is for people whose previous surgical valve replacement is now failing and who are at high risk for another open-heart surgery. Doctors will place the new valve inside the old one using a catheter thr…

This early study is testing a new device called the INNOVALVE system for people with a serious leak in their mitral heart valve. It is for patients who have symptoms and are considered at high risk for traditional open-heart surgery. The main goal is to see if the device is safe …

This study is testing a new medical monitoring device called HemoSphere Alta in adults having major heart or liver transplant surgery. The goal is to collect data from about 100 patients to help improve the device for future use. This is not a treatment study; it focuses on gathe…

This study aims to collect real-world information on how well a specific artificial aortic heart valve works over time. It will follow 500 patients in Germany who receive this valve as part of their standard medical care. The main goal is to monitor the valve's performance, inclu…

This study is testing a new, non-invasive blood pressure monitor called ClearSight NextGen. It uses finger cuffs and is being compared to standard monitoring devices during surgery. The goal is to collect data to help develop the new system for future use.