Growing heart valve could spare kids multiple surgeries

NCT ID NCT07466745

Recruiting now Disease control Sponsor: Edwards Lifesciences Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 11, 2026 · Updated 4 times

Summary

This study tests a special heart valve that can be adjusted to fit children as they grow. It involves 36 kids aged 1.5 to 16 years with congenital heart disease who need a new pulmonary valve. The valve is placed during surgery and can later be expanded without another operation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Autus Size-Adjustable Valve
What this could lead to: If it works, this valve could grow with the child, reducing the need for repeat surgeries.
What could go wrong: This is an early study with only 36 participants, so results may not apply to all children. Risks include device-related complications like valve thrombosis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

congenital heart disease pulmonary valve disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CONGENITAL HEART DISEASE

Contacts and locations

Locations

Boston Children's Hospital
NOT_YET_RECRUITING

Boston, Massachusetts, 02115, United States
Children's Healthcare of Atlanta
NOT_YET_RECRUITING

Atlanta, Georgia, 30322, United States
Children's Hospital Colorado
NOT_YET_RECRUITING

Aurora, Colorado, 80045, United States
Children's Hospital Los Angeles
NOT_YET_RECRUITING

Los Angeles, California, 90027, United States
Columbia University Irving Medical Center/New York Presbyterian Morgan Stanley Children's Hospital
NOT_YET_RECRUITING

New York, New York, 10032, United States
Duke University
NOT_YET_RECRUITING

Durham, North Carolina, 27703, United States
Nationwide Children's Hospital
NOT_YET_RECRUITING

Columbus, Ohio, 43205, United States
Seattle Children's Hospital
NOT_YET_RECRUITING

Seattle, Washington, 98105, United States
University of Michigan - Mott Children's Hospital
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Utah - Intermountain Primary Children's Hospital
NOT_YET_RECRUITING

Salt Lake City, Utah, 84113, United States

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