Which ablation works best for AFib with heart failure? new trial aims to find out
NCT ID NCT07153718
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study compares three catheter ablation strategies in 300 adults with persistent atrial fibrillation and heart failure. The goal is to see which approach best reduces the risk of death, hospitalization, or urgent visits due to worsening heart failure. Participants are randomly assigned to one of three ablation procedures, and their heart rhythm and outcomes are tracked over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
catheter ablation (a procedure to destroy abnormal heart tissue causing irregular rhythm)
What this could lead to
If successful, this could identify the best ablation approach to improve survival and reduce hospitalizations for people with both atrial fibrillation and heart failure.
What could go wrong
This is a mid-stage trial with 300 participants, so results may not apply to everyone. Ablation carries risks like bleeding, infection, or heart rhythm complications.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Affiliated Hospital of Jining Medical University
Jining, Shandong, 272000, China
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Changshu Hospital of Traditional Chinese Medicine
Changshu, Jiangsu, 215516, China
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Jinan City People's Hospital
Jinan, Shandong, 271100, China
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Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, 200127, China
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Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Jinan, Shandong, 250000, China
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Shanghai Jiao Tong University School of Medicine, Shanghai Chest Hospital
Shanghai, 200030, China
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The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, 430014, China
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The PLA Navy Anqing Hospital
Anqing, Anhui, 246000, China
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Xuzhou Central Hospital
Xuzhou, Jiangsu, 221009, China
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Yuhuan Second People's Hospital
Yuhuan, Zhejiang, 317600, China