Eye scans may reveal hidden clues about heart failure

NCT ID NCT05086978

First seen Jun 27, 2026 · Last updated Jul 23, 2026 · Updated 2 times

Summary

This pilot study at the Cleveland Clinic is testing whether a simple, non-invasive retinal camera can detect signs of heart failure severity. Researchers will compare eye images from 250 people with and without heart failure to see if blood vessel changes in the retina match disease progression and exercise capacity. If it works, this could lead to a new way to monitor heart failure without needles or expensive scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple, non-invasive eye test to help monitor heart failure severity and treatment response.
What could go wrong
This is an early pilot study with only 250 participants, so results may not apply broadly. It is observational and does not test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

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Other studies related to the condition(s) this trial covers.