Eye scans may reveal hidden clues about heart failure

NCT ID NCT05086978

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study at the Cleveland Clinic is testing whether a simple, non-invasive retinal camera can detect signs of heart failure severity. Researchers will compare eye images from 250 people with and without heart failure to see if blood vessel changes in the retina match disease progression and exercise capacity. If it works, this could lead to a new way to monitor heart failure without needles or expensive scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple, non-invasive eye test to help monitor heart failure severity and treatment response.

What could go wrong

This is an early pilot study with only 250 participants, so results may not apply broadly. It is observational and does not test a treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States