Could hearts from circulatory death donors expand transplant options?
NCT ID NCT05462041
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study tests whether hearts from donors who died from circulatory death (DCD) are as safe for transplant as hearts from brain-dead donors (DBD). About 40 adult heart transplant recipients will receive either a DCD or DBD heart. The goal is to see if using DCD hearts can safely increase the number of available donor hearts.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Donor heart transplantation technique (DCD with NRP or DPP vs DBD with cold storage)
- What this could lead to
- If successful, this could increase the number of hearts available for transplant, potentially saving more lives.
- What could go wrong
- This is a small pilot study, so results may not apply broadly. DCD hearts may carry higher risks of complications.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cedars Sinai Medical Center
Los Angeles, California, 90048, United States
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