Could hearts from circulatory death donors expand transplant options?

NCT ID NCT05462041

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests whether hearts from donors who died from circulatory death (DCD) are as safe for transplant as hearts from brain-dead donors (DBD). About 40 adult heart transplant recipients will receive either a DCD or DBD heart. The goal is to see if using DCD hearts can safely increase the number of available donor hearts.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Donor heart transplantation technique (DCD with NRP or DPP vs DBD with cold storage)

What this could lead to

If successful, this could increase the number of hearts available for transplant, potentially saving more lives.

What could go wrong

This is a small pilot study, so results may not apply broadly. DCD hearts may carry higher risks of complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States