Cedars-sinai Medical Center

This study is testing whether restricting eating to a 10-hour daily window during cancer treatment can reduce side effects and improve tumor response. Researchers are enrolling 175 adults with breast or rectal cancer who are receiving chemotherapy with curative intent. The goal i…

This study is testing if using common cholesterol-lowering drugs can help the body's own immune cells fight early prostate cancer. It involves 140 men with low-to-intermediate risk prostate cancer who are on active surveillance and scheduled for a biopsy. The goal is to see if lo…

This study is testing whether a special light treatment, applied to the forehead, can help people with early memory loss due to Alzheimer's disease. Researchers want to see if the light can improve thinking skills and reduce signs of brain inflammation. Participants will receive …

This study is testing if delivering healthy meals to patients' homes for 12 days after bone surgery helps them recover better. Researchers want to see if this reduces wound problems and improves lab results related to nutrition. The study will follow 75 adults who live in certain…

This study is testing whether adding a new immunotherapy drug called ivonescimab to standard chemotherapy before surgery is safe and more effective for people with early-stage triple-negative breast cancer (TNBC). About 34 participants will receive the drug combination for about …

This study is testing whether a 4-week course of an oral drug called seliciclib is safe and can help control the excess hormone production in adults with Cushing disease. It will involve about 13 people whose disease is newly diagnosed, has come back, or didn't go away after prev…

This study tests an experimental stem cell transplant for young people with severe Crohn's disease that hasn't responded to standard medications. Doctors wipe out the overactive immune cells and replace them with the patient's own blood stem cells, aiming to 'reset' the immune sy…

This study is testing if a combination of zinc and nicotinamide riboside supplements can help treat Idiopathic Pulmonary Fibrosis (IPF), a serious lung scarring disease. It aims to see if people with IPF can join and complete the entire trial from home, using video visits and loc…

This study is testing a special mobile app designed for Black pregnant women. The app provides culturally relevant tools to build self-advocacy skills, improve communication with doctors, and create a support network. Researchers want to see if using the app can help reduce depre…

This study is testing whether following a strict ketogenic diet (high-fat, very low-carb) alongside standard cancer treatment helps people with newly diagnosed glioblastoma live longer. Researchers will compare the keto diet to standard dietary advice in 170 patients over 18 week…

This study is testing whether using a computer navigation system makes a balloon procedure for chronic sinusitis more accurate and successful. Adults with chronic sinus infections who need surgery will have the procedure done on both sides—one side with the navigation guide and o…

This study compares two different heart ablation techniques used to treat paroxysmal atrial fibrillation. Researchers want to see which method causes less heating and potential injury to the nearby esophagus during the procedure. They'll measure temperature changes during treatme…

This study is testing if adding one of two behavior strategies to a standard weight loss program helps people lose more weight. The 'AVOID' strategy helps people change their home food environment, while the 'RESIST' strategy uses a game-like app to train impulse control. About 5…

This study is testing a new urine test to better detect bladder cancer in people who have small amounts of blood in their urine that can't be seen by the naked eye. The goal is to create a more accurate, non-invasive test that could help many patients avoid an uncomfortable camer…

This study is testing a new medical tool designed to collect fluid from the small intestine. Researchers want to see if this new 'capillary' catheter can collect samples faster and with less contamination than the standard tool used during routine endoscopies. The study involves …

This study is testing a new urine test that might help detect returning bladder cancer without needing invasive camera exams. Researchers will compare the new test against current methods in 300 people with a history of bladder cancer who are being monitored for recurrence. The g…

This study is testing a new urine test that aims to predict whether bladder cancer patients will respond to standard BCG immunotherapy. Currently, about half of patients don't benefit from BCG treatment, leading to additional therapies or bladder removal surgery. The test measure…

This study is testing whether a special fluorescent dye called CYTALUX can help surgeons see gastrointestinal cancer cells more clearly during surgery. The dye is injected before the operation and glows under special near-infrared light, potentially revealing cancer that might ot…

This study is testing an online decision aid called 'Protect Your Colon' to see if it helps people choose and complete a colon cancer screening test. Researchers will compare people who use the tool to those who receive standard care to see if it leads to more screenings. The goa…

This study is testing whether daily 15-minute virtual reality sessions can help prevent delirium in high-risk patients in the surgical intensive care unit (ICU). Participants will either receive standard ICU care or standard care plus calming VR experiences featuring nature scene…

This small pilot study is testing whether adding hands-on cooking classes makes a standard diabetes prevention program more appealing and easier for people to stick with. Researchers will work with 20 adults at risk for diabetes at two Los Angeles community health centers. The go…

This small early study is testing whether oral ketamine (a medication sometimes used for depression) can help reduce anxiety in people with pancreatic cancer. Twenty participants will try both ketamine and a placebo pill in random order to see if it's safe and tolerable. The main…

This study is testing a free, virtual support program called Family Foundations for people who are pregnant through fertility treatments like IVF. Participants and a support person (like a partner or friend) attend 9 online sessions over 6 months to build communication skills and…

This study is comparing different standard pain management plans used after gender-affirming surgery. Researchers want to find which methods best control pain while reducing the need for strong opioid medications and their unpleasant side effects. They will track pain levels, med…

This study is testing whether virtual reality (VR) can help reduce pain and improve quality of life for people with gastrointestinal cancers. Researchers will compare three approaches: VR that teaches pain management skills, VR designed to distract from pain, and a basic VR contr…

This study is testing if smelling lavender during certain awake ear, nose, and throat procedures helps reduce patient anxiety and pain. Researchers will compare lavender scent to an odorless placebo in about 184 adults. Participants will answer short surveys about their comfort a…

This pilot study is testing if a common cholesterol medication, simvastatin, can help reduce pain and improve daily life for adults with chronic or recurrent pancreatitis. It will involve 90 participants who will take either simvastatin or a placebo pill for six months. The main …

This study is testing whether a new type of fluticasone nasal spray, which uses a special 'exhalation' delivery system, can help people with chronic Eustachian tube dysfunction (ETD). ETD causes symptoms like ear pressure, fullness, and muffled hearing. Researchers will compare t…

This study is testing if wearing a simple nighttime finger splint helps people with trigger finger feel better after getting a cortisone injection. Researchers want to see if the splint reduces pain and improves hand function more than the injection alone. They are enrolling 146 …

This study is testing a one-time educational session designed to help people with gynecologic cancer and their caregivers manage the high costs of treatment. The 30-minute session, led by a trained educator, provides a guide and a cost tracker. Researchers want to see if this sup…

This study is testing if a special hospital discharge program that provides a continuous glucose monitor (CGM) can improve patient satisfaction and quality of life. It involves about 37 adults with Type 1 or Type 2 diabetes who use insulin and have not used a CGM recently. Resear…

This small, early-stage study is checking if it's practical to test a vitamin D-based medication called paricalcitol for chronic pancreatitis. It will involve 24 adults to see if the drug is well-tolerated and might improve their quality of life and pain. The main goal is to gath…

This study is testing whether giving doctors and patients AI-generated feedback after a prostate cancer consultation improves their conversations and helps patients make better treatment choices. About 283 men with newly diagnosed, localized prostate cancer will be enrolled. Doct…

This study aims to learn if it's safe to closely monitor very small thyroid cancers instead of having surgery right away. It will follow 216 people with these small tumors for up to 10 years to see if the cancer grows or spreads. The research also compares quality of life and anx…

This study aims to create a detailed map of the different types of cells in body fat from older adults with obesity. Researchers will compare how a lifestyle program and an experimental drug that targets 'senescent' or worn-out cells affect insulin sensitivity and metabolism. The…

This study aims to understand what factors predict when pituitary tumors might return after treatment. Researchers will follow 1,250 patients with confirmed pituitary disease for up to 20 years, collecting detailed information about their treatment and health outcomes. The goal i…