New nasal spray delivery could finally pop ear troubles away

NCT ID NCT05275686

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether a new nasal spray system that delivers fluticasone deeper into the nose can relieve Eustachian tube dysfunction (ETD) โ€” a condition causing ear pressure, popping, and muffled hearing. About 80 adults with chronic ETD will receive either the active spray or a placebo. The goal is to see if this improved delivery method works better than standard sprays.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cedars-Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

  • Indiana University

    RECRUITING

    Indianapolis, Indiana, 46202, United States

  • Ochsner Health System

    RECRUITING

    New Orleans, Louisiana, 70121, United States

  • Sacramento Ear, Nose & Throat

    RECRUITING

    Sacramento, California, 95661, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.