New study aims to cut opioid use in transgender surgery recovery
NCT ID NCT04979338
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study compares different nerve block techniques to manage pain after gender-affirming surgery in transgender adults. The goal is to find which method reduces pain and opioid use while minimizing side effects like nausea and urinary problems. Researchers will track pain levels, opioid consumption, and recovery quality in 640 participants.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bupivacaine with epinephrine (nerve blocks)
What this could lead to
If successful, this could establish a standard for safer, more effective pain control after gender-affirming surgeries, reducing opioid use and side effects.
What could go wrong
This is a Phase 3 trial, but it compares existing techniques, so no new drug is being tested. Results may not apply to all surgery types or hospitals.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cedars-Sinai Medical Center - North and South Towers
RECRUITINGLos Angeles, California, 90048, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••