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Major study to find best care paths for transgender people

NCT ID NCT05273112

Knowledge-focused Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will follow 400 transgender people over five years to see how different types of care—like hormone therapy, surgery, and mental health support—affect their quality of life. Researchers want to find out which care approaches work best. The goal is to improve and standardize care for transgender individuals.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could identify the most effective care paths for transgender people during medical transition, leading to better standardized support.
What could go wrong
This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not apply to all transgender populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 400 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2027

An estimate. Start dates often move.

Expected to finish

Apr 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

transgender people in medical transition

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * With a diagnosis of Gender Dysphoria according to DSM5 diagnostic criteria * Wishing to benefit from supportive care for their transition trajectory and addressing a care system represented by the collaborating centers participating in the study, * Willing to comply with all study procedures and duration, * Understanding and able to speak French. Exclusion Criteria: * Minor or adult under curatorship, under judicial protection, persons deprived of their liberty * Refusal to participate after clear and fair information from the study * Person with sexual reassignment surgery or with cross hormon therapy since two years.

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Conditions

The condition(s) this trial relates to.

Gender Dysphoria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gender dysphoria

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    13 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CHU de Bordeaux

    Bordeaux, France

  • CHU de Brest

    Brest, France

  • CHU de Caen

    Caen, France

  • CHU de Lille

    Lille, France

  • CHU de Lyon

    Lyon, France

  • CHU de Nice

    Nice, France

  • Centre Hospitalier Maison Blanche

    Paris, France

  • Centre Hospitalier Sainte-Anne

    Paris, France

  • Centre Hospitalier de Béziers

    Béziers, France

  • G..R.E.T.T.I.S

    Lyon, France

  • Hopital de la Conception - Marseille

    Marseille, France

  • Maison de Santé Lille Moulins

    Lille, France

  • Maison de Santé Lille Sud

    Lille, France

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