Cedars-sinai Medical Center

This study looks at whether a lower-dose version of standard chemo-radiation can work just as well for people with HPV-positive throat cancer after robotic surgery, while causing fewer side effects. About 40 patients will receive a tailored treatment plan based on their risk leve…

This early-stage study tests whether atezolizumab, a drug used for certain cancers, is safe and shows promise for treating idiopathic pulmonary fibrosis (IPF), a condition that causes lung scarring. About 24 adults aged 50 and older with confirmed IPF will receive the drug. Resea…

This study looks at whether women aged 65 and older with early-stage, estrogen-positive breast cancer can safely skip a sentinel node biopsy (a procedure to check if cancer has spread to lymph nodes) during their lumpectomy. The goal is to see if omitting this step leads to simil…

This study looks at whether terazosin, a drug usually used for high blood pressure, can slow the progression of Parkinson's disease. Researchers are following 15 people with early signs of Parkinson's or a related sleep disorder. They use special scans and symptom checks over 3 y…

This study tests whether adding the drug Thymoglobulin to standard anti-rejection medicines can prevent heart transplant complications. About 60 people receiving their first heart transplant will take part. Half will get Thymoglobulin for 5 days after surgery, and all will be mon…

This study tests whether a pharmacist-led medication review before and after hospital discharge can reduce the number of patients who need to return to the hospital or visit the ER within 30 days. It involves over 6,000 older adults (55+) who take many medications or specific hig…

This study tests a program to help older adults (65+) safely reduce unnecessary medications that may cause side effects. Researchers will use a risk-prediction tool to identify high-risk participants and then guide doctors in deprescribing. The goal is to see if this approach is …

This study is testing a new urine test that looks for specific markers of bladder cancer. The goal is to catch the disease early in people who are at high risk, such as those over 50 with a heavy smoking history. Researchers will follow 173 participants for up to 4 years to see h…

This study is testing a new urine test that looks for specific markers of bladder cancer. It involves 450 adults who have visible blood in their urine. The goal is to see if this simple test can accurately detect bladder cancer without needing a more invasive camera procedure cal…

This study compares two methods of giving the pain medicine EXPAREL during knee replacement surgery. About 40 adults will receive the medicine either as a targeted block or as a general injection around the knee. The goal is to see if both methods provide similar pain relief afte…

This study tests a culturally tailored mobile health program for 150 Black pregnant women to see if it reduces symptoms of depression, anxiety, and stress. Half of the participants receive the app, which teaches communication and self-advocacy skills and offers a support network.…

This early-phase trial tests whether giving focused radiation (radiosurgery) to a brain tumor before surgical removal helps protect healthy brain tissue and may eliminate the need for radiation after surgery. About 25 adults with brain metastases (tumors that spread from other ca…

This early-stage study tests whether injecting donated fat tissue into the small joints of the hand can safely reduce pain and improve function in people with early osteoarthritis. About 34 adults with hand arthritis will receive the injection and be monitored for changes in stre…

This study looks at whether a supervised exercise program is safe and practical for people with pancreatic cancer. Sixteen participants will attend exercise sessions before their main treatment. The goal is to see if at least half of them can stick with the program, and to check …

This study looks at how carvedilol, a medication usually used for heart conditions, affects brain scans over three years in 15 people who have early signs that may lead to Parkinson's disease. Participants have REM sleep behavior disorder and other risk factors. The goal is to be…

This study tests a new high-density microelectrode designed to record activity from individual brain cells in people with Parkinson's disease undergoing deep brain stimulation (DBS) surgery. The goal is to see if this new electrode works better than standard ones and is safe. Ten…

This study looks at how the brain learns, remembers, and makes decisions. Researchers will monitor brain activity in 200 epilepsy patients who are already undergoing brain monitoring for their condition. The goal is to better understand memory and thinking, which could help desig…

This study explores whether a new type of MRI (6D-MRI) can predict outcomes in people with pancreatic cancer. Researchers will scan 36 patients before and during chemotherapy to see if the images can show how well the treatment is working. The goal is to improve treatment plannin…

This study looks at 433 women with chest pain but no major blockages in their heart arteries. Researchers compare standard angiograms with noninvasive cardiac MRI to find problems in small heart arteries. The goal is to improve detection and understanding of heart disease in wome…

This study looks at whether terazosin, a drug used for high blood pressure, can change how the heart's nerves work in people who may be in the early stages of Parkinson's disease. Researchers are studying 15 adults aged 50-85 with REM sleep behavior disorder, a known risk factor …